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Intraspinal administration of interleukin-7 promotes neuronal apoptosis and limits functional recovery through JAK/STAT5 pathway following spinal cord injury.
Yuan, Xiaochen; Wu, Qingbin; Wang, Peng; Jing, Yingli; Yao, Haijiang; Tang, Yinshan; Han, Ruiqin; He, Weili; Li, Zhigang; Zhang, Honggang; Xiu, Ruijuan.
Affiliation
  • Yuan X; Institute of Microcirculation, Key Laboratory of Microcirculation, Ministry of Health, Chinese Academy of Medical Sciences & Peking Union Medical College, China.
  • Wu Q; Institute of Microcirculation, Key Laboratory of Microcirculation, Ministry of Health, Chinese Academy of Medical Sciences & Peking Union Medical College, China. Electronic address: 519706@163.com.
  • Wang P; Orthopedics Department, Hebei Provincial Hospital of Traditional Chinese Medicine, China.
  • Jing Y; China Rehabilitation Science Institute, China Rehabilitation Research Center, Center of Neural Injury and Repair, Beijing Institute for Brain Disorders, Beijing Key Laboratory of Neural Injury and Rehabilitation, China.
  • Yao H; Treatment Center of TCM, Beijing Bo'ai Hospital, China Rehabilitation Research Center, School of Rehabilitation, Capital Medical University, China.
  • Tang Y; Department of Rehabilitation in Traditional Chinese Medicine, The Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou, China.
  • Han R; Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, China.
  • He W; Infections Department, Dongzhimen Hospital Beijing University of Chinese Medicine, China.
  • Li Z; School of Acupuncture, Moxibustion and Tuina, Beijing University of Chinese Medicine, China. Electronic address: lizhigang620620@163.com.
  • Zhang H; Institute of Microcirculation, Key Laboratory of Microcirculation, Ministry of Health, Chinese Academy of Medical Sciences & Peking Union Medical College, China. Electronic address: zhanghg1966126@126.com.
  • Xiu R; Institute of Microcirculation, Key Laboratory of Microcirculation, Ministry of Health, Chinese Academy of Medical Sciences & Peking Union Medical College, China.
Biochem Biophys Res Commun ; 514(3): 1023-1029, 2019 06 30.
Article in En | MEDLINE | ID: mdl-31068251
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spinal Cord Injuries / Signal Transduction / Interleukin-7 / Apoptosis / Recovery of Function / STAT5 Transcription Factor / Janus Kinases Limits: Animals Language: En Journal: Biochem Biophys Res Commun Year: 2019 Type: Article Affiliation country: China
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spinal Cord Injuries / Signal Transduction / Interleukin-7 / Apoptosis / Recovery of Function / STAT5 Transcription Factor / Janus Kinases Limits: Animals Language: En Journal: Biochem Biophys Res Commun Year: 2019 Type: Article Affiliation country: China