Impacts of Polymeric Additives on Nucleation and Crystal Growth of Indomethacin from Supersaturated Solutions.

Cheng, Hui; Mao, Liang; Zhang, Shuai; Lv, Huixia

Cheng, Hui; Mao, Liang; Zhang, Shuai; Lv, Huixia.

Affiliation

Cheng H; Pharmaceutical Development Services, Shanghai STA Pharmaceutical R&D Co., Ltd, Shanghai, China.
Mao L; School of Pharmacy, China Pharmaceutical University, Nanjing, China.
Zhang S; Pharmaceutical Development Services, Shanghai STA Pharmaceutical R&D Co., Ltd, Shanghai, China.
Lv H; Pharmaceutical Development Services, Shanghai STA Pharmaceutical R&D Co., Ltd, Shanghai, China. zhang_shuai0103@wuxiapptec.com.

AAPS PharmSciTech ; 20(5): 193, 2019 May 21.

Article in En | MEDLINE | ID: mdl-31115746

Subject(s)

Anti-Inflammatory Agents, Non-Steroidal/chemical synthesis; Indomethacin/chemical synthesis; Polymers/chemical synthesis; Anti-Inflammatory Agents, Non-Steroidal/pharmacokinetics; Crystallization/methods; Drug Compounding; Hypromellose Derivatives/chemical synthesis; Hypromellose Derivatives/pharmacokinetics; Indomethacin/pharmacokinetics; Pharmaceutical Solutions/chemical synthesis; Pharmaceutical Solutions/pharmacokinetics; Polymers/pharmacokinetics; Povidone/chemical synthesis; Povidone/pharmacokinetics; Solubility

Key words

crystal growth; indomethacin; nucleation; polymeric additives; supersaturated solution

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymers / Anti-Inflammatory Agents, Non-Steroidal / Indomethacin Type of study: Prognostic_studies Language: En Journal: AAPS PharmSciTech Journal subject: FARMACOLOGIA Year: 2019 Type: Article Affiliation country: China

Fulltext

XML

PubMed Links

Search on Google