Screening of angiogenesis inhibitors using a 3D vascular microfluidic chip to achieve contraception.

Si, Qingrui; Liu, Ran

Si, Qingrui; Liu, Ran.

Affiliation

Si Q; Department of Biomedical Engineering, School of Medicine, Tsinghua University of China, Beijing, 100084, Beijing, China.
Liu R; Department of Biomedical Engineering, School of Medicine, Tsinghua University of China, Beijing, 100084, Beijing, China. Electronic address: liuran@tsinghua.edu.cn.

Biochem Biophys Res Commun ; 515(1): 92-98, 2019 07 12.

Article in En | MEDLINE | ID: mdl-31128919

Subject(s)

Angiogenesis Inhibitors/pharmacology; Contraception; Embryo Implantation/drug effects; Embryo, Mammalian/drug effects; Fertilization/drug effects; Microfluidics/methods; Angiogenesis Inhibitors/isolation & purification; Animals; Cells, Cultured; Drug Evaluation, Preclinical/methods; Embryo, Mammalian/diagnostic imaging; Embryo, Mammalian/embryology; Female; Human Umbilical Vein Endothelial Cells/cytology; Human Umbilical Vein Endothelial Cells/drug effects; Human Umbilical Vein Endothelial Cells/physiology; Humans; Magnetic Resonance Imaging/methods; Male; Mice, Inbred ICR

Key words

3D biomimetic blood vessel; Angiogenesis; Contraception; Drug screening; Microfluidic chip

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Embryo Implantation / Contraception / Angiogenesis Inhibitors / Microfluidics / Embryo, Mammalian / Fertilization Type of study: Diagnostic_studies / Screening_studies Limits: Animals / Female / Humans / Male Language: En Journal: Biochem Biophys Res Commun Year: 2019 Type: Article Affiliation country: China

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