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Regulatory T cells engineered with a novel insulin-specific chimeric antigen receptor as a candidate immunotherapy for type 1 diabetes.
Tenspolde, Michel; Zimmermann, Katharina; Weber, Leonie C; Hapke, Martin; Lieber, Maren; Dywicki, Janine; Frenzel, Andre; Hust, Michael; Galla, Melanie; Buitrago-Molina, Laura E; Manns, Michael P; Jaeckel, Elmar; Hardtke-Wolenski, Matthias.
Affiliation
  • Tenspolde M; Dept. of Gastroenterology, Hepatology & Endocrinology, Hannover Medical School, Hannover, Germany.
  • Zimmermann K; Dept. of Gastroenterology, Hepatology & Endocrinology, Hannover Medical School, Hannover, Germany.
  • Weber LC; Dept. of Gastroenterology and Hepatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
  • Hapke M; Dept. of Gastroenterology, Hepatology & Endocrinology, Hannover Medical School, Hannover, Germany.
  • Lieber M; Dept. of Gastroenterology, Hepatology & Endocrinology, Hannover Medical School, Hannover, Germany.
  • Dywicki J; Dept. of Gastroenterology, Hepatology & Endocrinology, Hannover Medical School, Hannover, Germany.
  • Frenzel A; Technische Universität Braunschweig, Institut für Biochemie, Biotechnologie und Bioinformatik, Abteilung Biotechnologie, Braunschweig, Germany; YUMAB GmbH, Science Campus Braunschweig-Süd, Inhoffenstr. 7, 38124, Braunschweig, Germany.
  • Hust M; Technische Universität Braunschweig, Institut für Biochemie, Biotechnologie und Bioinformatik, Abteilung Biotechnologie, Braunschweig, Germany; YUMAB GmbH, Science Campus Braunschweig-Süd, Inhoffenstr. 7, 38124, Braunschweig, Germany.
  • Galla M; Institute of Experimental Haematology, Hannover Medical School, Hannover, Germany.
  • Buitrago-Molina LE; Dept. of Gastroenterology and Hepatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
  • Manns MP; Dept. of Gastroenterology, Hepatology & Endocrinology, Hannover Medical School, Hannover, Germany.
  • Jaeckel E; Dept. of Gastroenterology, Hepatology & Endocrinology, Hannover Medical School, Hannover, Germany.
  • Hardtke-Wolenski M; Dept. of Gastroenterology, Hepatology & Endocrinology, Hannover Medical School, Hannover, Germany; Dept. of Gastroenterology and Hepatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. Electronic address: Matthias.Hardtke-Wolenski@uk-essen.de.
J Autoimmun ; 103: 102289, 2019 09.
Article in En | MEDLINE | ID: mdl-31176558
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Antigen, T-Cell / T-Lymphocytes, Cytotoxic / Immunotherapy, Adoptive / T-Lymphocytes, Regulatory / Diabetes Mellitus, Type 1 / Receptors, Chimeric Antigen Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Autoimmun Journal subject: ALERGIA E IMUNOLOGIA Year: 2019 Type: Article Affiliation country: Germany
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Antigen, T-Cell / T-Lymphocytes, Cytotoxic / Immunotherapy, Adoptive / T-Lymphocytes, Regulatory / Diabetes Mellitus, Type 1 / Receptors, Chimeric Antigen Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Autoimmun Journal subject: ALERGIA E IMUNOLOGIA Year: 2019 Type: Article Affiliation country: Germany