Comparative Analysis of Pentacyclic Triterpenic Acid Compositions in Oleogum Resins of Different <i>Boswellia</i> Species and Their In Vitro Cytotoxicity against Treatment-Resistant Human Breast Cancer Cells.

Schmiech, Michael; Lang, Sophia J; Werner, Katharina; Rashan, Luay J; Syrovets, Tatiana; Simmet, Thomas

Comparative Analysis of Pentacyclic Triterpenic Acid Compositions in Oleogum Resins of Different Boswellia Species and Their In Vitro Cytotoxicity against Treatment-Resistant Human Breast Cancer Cells.

Schmiech, Michael; Lang, Sophia J; Werner, Katharina; Rashan, Luay J; Syrovets, Tatiana; Simmet, Thomas.

Affiliation

Schmiech M; Institute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University, 89081 Ulm, Germany. michael.schmiech@uni-ulm.de.
Lang SJ; Institute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University, 89081 Ulm, Germany. sophia.lang@uni-ulm.de.
Werner K; Institute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University, 89081 Ulm, Germany. katharina.werner@uni-ulm.de.
Rashan LJ; Medicinal Plants Division, Research Center, Dhofar University, Salalah 211, Oman. luayrashan@yahoo.com.
Syrovets T; Institute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University, 89081 Ulm, Germany. tatiana.syrovets@uni-ulm.de.
Simmet T; Institute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University, 89081 Ulm, Germany. thomas.simmet@uni-ulm.de.

Molecules ; 24(11)2019 Jun 07.

Article in En | MEDLINE | ID: mdl-31181656

Subject(s)

Antineoplastic Agents, Phytogenic/analysis; Boswellia/chemistry; Breast Neoplasms/drug therapy; Pentacyclic Triterpenes/analysis; Resins, Plant/analysis; Antineoplastic Agents, Phytogenic/pharmacology; Cell Line, Tumor; Cell Proliferation/drug effects; Cell Survival/drug effects; Chromatography, High Pressure Liquid; Drug Resistance, Neoplasm/drug effects; Female; Humans; Pentacyclic Triterpenes/pharmacology; Resins, Plant/pharmacology; Tandem Mass Spectrometry; Triterpenes/isolation & purification; Triterpenes/pharmacology

Key words

Boswellia; Boswellia occulta; MDA-MB-231; boswellic acid; breast cancer; frankincense; lupeolic acid; pentacyclic triterpenic acid

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Resins, Plant / Breast Neoplasms / Boswellia / Pentacyclic Triterpenes / Antineoplastic Agents, Phytogenic Limits: Female / Humans Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2019 Type: Article Affiliation country: Germany

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