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Synthesis and pharmacological evaluation of novel N-Mannich bases derived from 5,5-diphenyl and 5,5-di(propan-2-yl)imidazolidine-2,4-dione core.
Czopek, Anna; Byrtus, Hanna; Zagórska, Agnieszka; Rychtyk, Joanna; Góra, Malgorzata; Salat, Kinga; Rapacz, Anna; Obniska, Jolanta.
Affiliation
  • Czopek A; Department of Medicinal Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna St., 30-688 Krakow, Poland. Electronic address: anna.czopek@uj.edu.pl.
  • Byrtus H; Department of Medicinal Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna St., 30-688 Krakow, Poland.
  • Zagórska A; Department of Medicinal Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna St., 30-688 Krakow, Poland.
  • Rychtyk J; Department of Medicinal Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna St., 30-688 Krakow, Poland.
  • Góra M; Department of Medicinal Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna St., 30-688 Krakow, Poland.
  • Salat K; Department of Pharmacodynamics, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna St., 30-688 Krakow, Poland.
  • Rapacz A; Department of Pharmacodynamics, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna St., 30-688 Krakow, Poland.
  • Obniska J; Department of Medicinal Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna St., 30-688 Krakow, Poland.
Bioorg Med Chem Lett ; 29(16): 2387-2392, 2019 08 15.
Article in En | MEDLINE | ID: mdl-31208765
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pain / Seizures / Imidazolidines / Mannich Bases / Anticonvulsants Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2019 Type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pain / Seizures / Imidazolidines / Mannich Bases / Anticonvulsants Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2019 Type: Article