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Soft culture substrates favor stem-like cellular phenotype and facilitate reprogramming of human mesenchymal stem/stromal cells (hMSCs) through mechanotransduction.
Gerardo, Heloísa; Lima, Ana; Carvalho, João; Ramos, João R D; Couceiro, Sofia; Travasso, Rui D M; Pires das Neves, Ricardo; Grãos, Mário.
Affiliation
  • Gerardo H; CNC - Center for Neuroscience and Cell Biology, University of Coimbra, UC-Biotech Building, Biocant Park, Cantanhede, Portugal.
  • Lima A; CNC - Center for Neuroscience and Cell Biology, University of Coimbra, UC-Biotech Building, Biocant Park, Cantanhede, Portugal.
  • Carvalho J; Faculty of Science and Technology, University Nova of Lisbon (MIT-Portugal PhD Program), Caparica, Portugal.
  • Ramos JRD; Centro de Física da Universidade de Coimbra (CFisUC), Department of Physics, University of Coimbra, Coimbra, Portugal.
  • Couceiro S; Max Planck Institute for Dynamics and Self-Organization, Göttingen, Germany.
  • Travasso RDM; Stemlab S.A. (Crioestaminal), Biocant Park, Cantanhede, Portugal.
  • Pires das Neves R; Centro de Física da Universidade de Coimbra (CFisUC), Department of Physics, University of Coimbra, Coimbra, Portugal.
  • Grãos M; CNC - Center for Neuroscience and Cell Biology, University of Coimbra, UC-Biotech Building, Biocant Park, Cantanhede, Portugal. ricardo.neves@uc-biotech.pt.
Sci Rep ; 9(1): 9086, 2019 06 24.
Article in En | MEDLINE | ID: mdl-31235788
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenotype / Mechanotransduction, Cellular / Cellular Reprogramming / Mesenchymal Stem Cells Limits: Humans Language: En Journal: Sci Rep Year: 2019 Type: Article Affiliation country: Portugal
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenotype / Mechanotransduction, Cellular / Cellular Reprogramming / Mesenchymal Stem Cells Limits: Humans Language: En Journal: Sci Rep Year: 2019 Type: Article Affiliation country: Portugal