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Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss.
György, Bence; Nist-Lund, Carl; Pan, Bifeng; Asai, Yukako; Karavitaki, K Domenica; Kleinstiver, Benjamin P; Garcia, Sara P; Zaborowski, Mikolaj P; Solanes, Paola; Spataro, Sofia; Schneider, Bernard L; Joung, J Keith; Géléoc, Gwenaëlle S G; Holt, Jeffrey R; Corey, David P.
Affiliation
  • György B; Department of Neurobiology, Harvard Medical School, Boston, MA, USA.
  • Nist-Lund C; Department of Neurology, The Massachusetts General Hospital, Boston, MA, USA.
  • Pan B; Institute of Molecular and Clinical Ophthalmology Basel, Basel, Switzerland.
  • Asai Y; Departments of Otolaryngology & Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.
  • Karavitaki KD; Departments of Otolaryngology & Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.
  • Kleinstiver BP; Departments of Otolaryngology & Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.
  • Garcia SP; Department of Neurobiology, Harvard Medical School, Boston, MA, USA.
  • Zaborowski MP; Molecular Pathology Unit, Center for Cancer Research, Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA.
  • Solanes P; Center for Genomic Medicine and Department of Pathology, Massachusetts General Hospital, Boston, MA, USA.
  • Spataro S; Department of Pathology, Harvard Medical School, Boston, MA, USA.
  • Schneider BL; Molecular Pathology Unit, Center for Cancer Research, Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA.
  • Joung JK; Department of Pathology, Harvard Medical School, Boston, MA, USA.
  • Géléoc GSG; Department of Neurology, The Massachusetts General Hospital, Boston, MA, USA.
  • Holt JR; Department of Gynecology, Obstetrics and Gynecologic Oncology, Division of Gynecologic Oncology, Poznan University of Medical Sciences, Poznan, Poland.
  • Corey DP; Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Nat Med ; 25(7): 1123-1130, 2019 07.
Article in En | MEDLINE | ID: mdl-31270503
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alleles / Gene Editing / Hearing Loss, Sensorineural / Membrane Proteins Limits: Animals / Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2019 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alleles / Gene Editing / Hearing Loss, Sensorineural / Membrane Proteins Limits: Animals / Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2019 Type: Article Affiliation country: United States