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First platinum(II)-based metal-organic linker technology (Lx®) for a plug-and-play development of antibody-drug conjugates (ADCs).
Merkul, Eugen; Sijbrandi, Niels J; Muns, Joey A; Aydin, Ibrahim; Adamzek, Kevin; Houthoff, Hendrik-Jan; Nijmeijer, Bart; Van Dongen, Guus A M S.
Affiliation
  • Merkul E; a Research and Development Department, LinXis BV , Amsterdam , The Netherlands.
  • Sijbrandi NJ; a Research and Development Department, LinXis BV , Amsterdam , The Netherlands.
  • Muns JA; a Research and Development Department, LinXis BV , Amsterdam , The Netherlands.
  • Aydin I; a Research and Development Department, LinXis BV , Amsterdam , The Netherlands.
  • Adamzek K; a Research and Development Department, LinXis BV , Amsterdam , The Netherlands.
  • Houthoff HJ; a Research and Development Department, LinXis BV , Amsterdam , The Netherlands.
  • Nijmeijer B; a Research and Development Department, LinXis BV , Amsterdam , The Netherlands.
  • Van Dongen GAMS; b Department of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Universiteit , Amsterdam , The Netherlands.
Expert Opin Drug Deliv ; 16(8): 783-793, 2019 08.
Article in En | MEDLINE | ID: mdl-31327255

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Organoplatinum Compounds / Immunoconjugates / Trastuzumab / Aminobenzoates / Antineoplastic Agents Limits: Animals Language: En Journal: Expert Opin Drug Deliv Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2019 Type: Article Affiliation country: Netherlands

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Organoplatinum Compounds / Immunoconjugates / Trastuzumab / Aminobenzoates / Antineoplastic Agents Limits: Animals Language: En Journal: Expert Opin Drug Deliv Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2019 Type: Article Affiliation country: Netherlands