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Distinct HR expression patterns significantly affect the clinical behavior of metastatic HER2+ breast cancer and degree of benefit from novel anti-HER2 agents in the real world setting.
Pizzuti, Laura; Krasniqi, Eriseld; Barchiesi, Giacomo; Della Giulia, Marina; Izzo, Fiorentino; Sanguineti, Giuseppe; Marchetti, Paolo; Mazzotta, Marco; Giusti, Raffaele; Botticelli, Andrea; Gamucci, Teresa; Natoli, Clara; Grassadonia, Antonino; Tinari, Nicola; Iezzi, Laura; Tomao, Silverio; Tomao, Federica; Tonini, Giuseppe; Santini, Daniele; Astone, Antonio; Michelotti, Andrea; De Angelis, Claudia; Mentuccia, Lucia; Vaccaro, Angela; Magnolfi, Emanuela; Gelibter, Alain; Magri, Valentina; Cortesi, Enrico; D'Onofrio, Loretta; Cassano, Alessandra; Rossi, Ernesto; Cazzaniga, Marina; Moscetti, Luca; Omarini, Claudia; Piacentini, Federico; Fabbri, Maria A; Scinto, Angelo F; Corsi, Domenico; Carbognin, Luisa; Bria, Emilio; La Verde, Nicla; Samaritani, Riccardo; Garufi, Carlo; Barni, Sandro; Mirabelli, Rosanna; Sarmiento, Roberta; Veltri, Enzo M; D'Auria, Giuliana; Paris, Ida; Giotta, Francesco.
Affiliation
  • Pizzuti L; Division of Medical Oncology 2, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
  • Krasniqi E; Division of Medical Oncology 2, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
  • Barchiesi G; Division of Medical Oncology 2, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
  • Della Giulia M; Division of Medical Oncology 2, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
  • Izzo F; Division of Medical Oncology 2, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
  • Sanguineti G; Department of Radiation Oncology, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
  • Marchetti P; Medical Oncology Unit, Azienda Ospedaliera Universitaria Sant'Andrea, Rome, Italy.
  • Mazzotta M; Medical Oncology Unit B, Policlinico Umberto I, Rome, Italy.
  • Giusti R; Medical Oncology Unit, Azienda Ospedaliera Universitaria Sant'Andrea, Rome, Italy.
  • Botticelli A; Medical Oncology Unit, Azienda Ospedaliera Universitaria Sant'Andrea, Rome, Italy.
  • Gamucci T; Medical Oncology Unit B, Policlinico Umberto I, Rome, Italy.
  • Natoli C; Medical Oncology, Sandro Pertini Hospital, Rome, Italy.
  • Grassadonia A; Department of Medical, Oral and Biotechnological Sciences, Centro Scienze dell'Invecchiamento e Medicina Traslazionale -CeSI-MeT, Chieti, Italy.
  • Tinari N; Department of Medical, Oral and Biotechnological Sciences, Centro Scienze dell'Invecchiamento e Medicina Traslazionale -CeSI-MeT, Chieti, Italy.
  • Iezzi L; Department of Medical, Oral and Biotechnological Sciences, Centro Scienze dell'Invecchiamento e Medicina Traslazionale -CeSI-MeT, Chieti, Italy.
  • Tomao S; Department of Medical, Oral and Biotechnological Sciences, Centro Scienze dell'Invecchiamento e Medicina Traslazionale -CeSI-MeT, Chieti, Italy.
  • Tomao F; Department of Radiological, Oncological and Anatomo-Pathological Sciences, 'Sapienza' University of Rome, Policlinico Umberto I, Rome, Italy.
  • Tonini G; Department of Gynecology-Obstetrics and Urology, "Sapienza" University of Rome, Rome, Italy.
  • Santini D; Department of Oncology, University Campus Biomedico of Rome, Rome, Italy.
  • Astone A; Department of Oncology, University Campus Biomedico of Rome, Rome, Italy.
  • Michelotti A; Division of Medical Oncology, Villa San Pietro Hospital, Rome, Italy.
  • De Angelis C; UO Oncologia Medica I, S. Chiara Hospital, Dipartimentodi Oncologia, Dei Trapianti e Delle Nuove Tecnologie, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy.
  • Mentuccia L; UO Oncologia Medica I, S. Chiara Hospital, Dipartimentodi Oncologia, Dei Trapianti e Delle Nuove Tecnologie, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy.
  • Vaccaro A; Medical Oncology Unit, ASL Frosinone, Frosinone, Italy.
  • Magnolfi E; Medical Oncology Unit, ASL Frosinone, Frosinone, Italy.
  • Gelibter A; Medical Oncology Unit, ASL Frosinone, Frosinone, Italy.
  • Magri V; Medical Oncology Unit B, Policlinico Umberto I, Rome, Italy.
  • Cortesi E; Medical Oncology Unit B, Policlinico Umberto I, Rome, Italy.
  • D'Onofrio L; Medical Oncology Unit B, Policlinico Umberto I, Rome, Italy.
  • Cassano A; Department of Oncology, University Campus Biomedico of Rome, Rome, Italy.
  • Rossi E; Department of Medical Oncology, Policlinico Universitario "A. Gemelli", Rome, Italy.
  • Cazzaniga M; Universita Cattolica del Sacro Cuore, Roma.
  • Moscetti L; Department of Medical Oncology, Policlinico Universitario "A. Gemelli", Rome, Italy.
  • Omarini C; Research Unit Phase I trials and Oncology Unit, ASST Monza, Monza, Italy.
  • Piacentini F; Division of Medical Oncology, Department of Oncology and Hematology, University Hospital of Modena, Modena, Italy.
  • Fabbri MA; Division of Medical Oncology, Department of Oncology and Hematology, University Hospital of Modena, Modena, Italy.
  • Scinto AF; Division of Medical Oncology, Department of Oncology and Hematology, University Hospital of Modena, Modena, Italy.
  • Corsi D; Medical Oncology Unit, Belcolle Hospital, Viterbo, Italy.
  • Carbognin L; Medical Oncology Unit, Fatebenefratelli Hospital, Rome, Italy.
  • Bria E; Medical Oncology Unit, Fatebenefratelli Hospital, Rome, Italy.
  • La Verde N; Gynecology Oncology Unit, Catholic University of the Sacred Heart, Rome, Italy.
  • Samaritani R; Department of Medical Oncology, Policlinico Universitario "A. Gemelli", Rome, Italy.
  • Garufi C; Universita Cattolica del Sacro Cuore, Roma.
  • Barni S; Oncology Unit, ASST Fatebenefratelli Sacco Presidio Ospedaliero Fatebenefratelli, Milano, Italy.
  • Mirabelli R; Medical Oncology Unit, "Regina Margherita" Hospital, Rome, Italy.
  • Sarmiento R; Division of Medical Oncology, Pescara Hospital, Pescara, Italy.
  • Veltri EM; Department of Oncology, Oncology Unit, ASST Bergamo Ovest, Treviglio, Italy.
  • D'Auria G; Department of Hematology & Oncology, Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy.
  • Paris I; Oncology Unit, San Filippo Neri Hospital, Rome, Italy.
  • Giotta F; Oncology Unit, S. Maria Goretti Hospital, Latina, Italy.
Int J Cancer ; 146(7): 1917-1929, 2020 04 01.
Article in En | MEDLINE | ID: mdl-31330065
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Receptors, Progesterone / Receptors, Estrogen / Gene Expression Regulation, Neoplastic / Receptor, ErbB-2 Type of study: Prognostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Middle aged Language: En Journal: Int J Cancer Year: 2020 Type: Article Affiliation country: Italy
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Receptors, Progesterone / Receptors, Estrogen / Gene Expression Regulation, Neoplastic / Receptor, ErbB-2 Type of study: Prognostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Middle aged Language: En Journal: Int J Cancer Year: 2020 Type: Article Affiliation country: Italy