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Absence of Pharmacokinetic Interactions between the Bruton's Tyrosine Kinase Inhibitor Fenebrutinib and Methotrexate.
Jones, Nicholas Steven; Winter, Helen; Katsumoto, Tamiko R; Florero, Marilyn; Murray, Elaine; Walker, Helen; Singh, Nand; Chinn, Leslie W.
Affiliation
  • Jones NS; Clinical Science (N.J., T.K., M.F.), Clinical Pharmacology (H.Wi., L.C.), and Safety Science (E.M.), Genentech, Inc., South San Francisco, California; and Quotient Sciences, Ruddington, Nottingham, United Kingdom (H.Wa., N.S.).
  • Winter H; Clinical Science (N.J., T.K., M.F.), Clinical Pharmacology (H.Wi., L.C.), and Safety Science (E.M.), Genentech, Inc., South San Francisco, California; and Quotient Sciences, Ruddington, Nottingham, United Kingdom (H.Wa., N.S.).
  • Katsumoto TR; Clinical Science (N.J., T.K., M.F.), Clinical Pharmacology (H.Wi., L.C.), and Safety Science (E.M.), Genentech, Inc., South San Francisco, California; and Quotient Sciences, Ruddington, Nottingham, United Kingdom (H.Wa., N.S.).
  • Florero M; Clinical Science (N.J., T.K., M.F.), Clinical Pharmacology (H.Wi., L.C.), and Safety Science (E.M.), Genentech, Inc., South San Francisco, California; and Quotient Sciences, Ruddington, Nottingham, United Kingdom (H.Wa., N.S.).
  • Murray E; Clinical Science (N.J., T.K., M.F.), Clinical Pharmacology (H.Wi., L.C.), and Safety Science (E.M.), Genentech, Inc., South San Francisco, California; and Quotient Sciences, Ruddington, Nottingham, United Kingdom (H.Wa., N.S.).
  • Walker H; Clinical Science (N.J., T.K., M.F.), Clinical Pharmacology (H.Wi., L.C.), and Safety Science (E.M.), Genentech, Inc., South San Francisco, California; and Quotient Sciences, Ruddington, Nottingham, United Kingdom (H.Wa., N.S.).
  • Singh N; Clinical Science (N.J., T.K., M.F.), Clinical Pharmacology (H.Wi., L.C.), and Safety Science (E.M.), Genentech, Inc., South San Francisco, California; and Quotient Sciences, Ruddington, Nottingham, United Kingdom (H.Wa., N.S.).
  • Chinn LW; Clinical Science (N.J., T.K., M.F.), Clinical Pharmacology (H.Wi., L.C.), and Safety Science (E.M.), Genentech, Inc., South San Francisco, California; and Quotient Sciences, Ruddington, Nottingham, United Kingdom (H.Wa., N.S.) chinn.leslie@gene.com.
J Pharmacol Exp Ther ; 371(1): 202-207, 2019 10.
Article in En | MEDLINE | ID: mdl-31371481
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperazines / Pyridones / Methotrexate / Antirheumatic Agents / Protein Kinase Inhibitors Limits: Adult / Humans / Male / Middle aged Language: En Journal: J Pharmacol Exp Ther Year: 2019 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperazines / Pyridones / Methotrexate / Antirheumatic Agents / Protein Kinase Inhibitors Limits: Adult / Humans / Male / Middle aged Language: En Journal: J Pharmacol Exp Ther Year: 2019 Type: Article