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Complex DDI by Fenebrutinib and the Use of Transporter Endogenous Biomarkers to Elucidate the Mechanism of DDI.
Jones, Nicholas S; Yoshida, Kenta; Salphati, Laurent; Kenny, Jane R; Durk, Matthew R; Chinn, Leslie W.
Affiliation
  • Jones NS; Clinical Science, Genentech, Inc., South San Francisco, California, USA.
  • Yoshida K; Clinical Pharmacology, Genentech, Inc., South San Francisco, California, USA.
  • Salphati L; Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California, USA.
  • Kenny JR; Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California, USA.
  • Durk MR; Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California, USA.
  • Chinn LW; Clinical Pharmacology, Genentech, Inc., South San Francisco, California, USA.
Clin Pharmacol Ther ; 107(1): 269-277, 2020 01.
Article in En | MEDLINE | ID: mdl-31376152
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperazines / Pyridones / Protein Kinase Inhibitors / Cytochrome P-450 CYP3A / ATP Binding Cassette Transporter, Subfamily G, Member 2 / Neoplasm Proteins Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Clin Pharmacol Ther Year: 2020 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperazines / Pyridones / Protein Kinase Inhibitors / Cytochrome P-450 CYP3A / ATP Binding Cassette Transporter, Subfamily G, Member 2 / Neoplasm Proteins Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Clin Pharmacol Ther Year: 2020 Type: Article Affiliation country: United States