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Toxoplasmosis as an Early Complication of Allogeneic Hematopoietic Cell Transplantation.
Robin, Christine; Leclerc, Mathieu; Angebault, Cécile; Redjoul, Rabah; Beckerich, Florence; Cabanne, Ludovic; Foulet, Francoise; Pautas, Cécile; Toma, Andréa; Maury, Sébastien; Botterel, Francoise; Cordonnier, Catherine.
Affiliation
  • Robin C; Assistance Publique-Hôpitaux de Paris, Henri Mondor Hospital, Department of Hematology and Cellular Therapy, Créteil, France; University Paris-Est Créteil (UPEC), Créteil, France. Electronic address: christine.robin@aphp.fr.
  • Leclerc M; Assistance Publique-Hôpitaux de Paris, Henri Mondor Hospital, Department of Hematology and Cellular Therapy, Créteil, France; University Paris-Est Créteil (UPEC), Créteil, France.
  • Angebault C; University Paris-Est Créteil (UPEC), Créteil, France; Parasitology Unit, Microbiology Department, Henri Mondor Hospital, Créteil, France.
  • Redjoul R; Assistance Publique-Hôpitaux de Paris, Henri Mondor Hospital, Department of Hematology and Cellular Therapy, Créteil, France.
  • Beckerich F; Assistance Publique-Hôpitaux de Paris, Henri Mondor Hospital, Department of Hematology and Cellular Therapy, Créteil, France.
  • Cabanne L; Assistance Publique-Hôpitaux de Paris, Henri Mondor Hospital, Department of Hematology and Cellular Therapy, Créteil, France.
  • Foulet F; Parasitology Unit, Microbiology Department, Henri Mondor Hospital, Créteil, France.
  • Pautas C; Assistance Publique-Hôpitaux de Paris, Henri Mondor Hospital, Department of Hematology and Cellular Therapy, Créteil, France.
  • Toma A; Assistance Publique-Hôpitaux de Paris, Henri Mondor Hospital, Department of Hematology and Cellular Therapy, Créteil, France.
  • Maury S; Assistance Publique-Hôpitaux de Paris, Henri Mondor Hospital, Department of Hematology and Cellular Therapy, Créteil, France; University Paris-Est Créteil (UPEC), Créteil, France.
  • Botterel F; University Paris-Est Créteil (UPEC), Créteil, France; Parasitology Unit, Microbiology Department, Henri Mondor Hospital, Créteil, France; EA Dynamyc UPEC, Ecole Nationale Vétérinaire d'Alfort (ENVA), Faculté de Médecine de Créteil, Créteil, France.
  • Cordonnier C; Assistance Publique-Hôpitaux de Paris, Henri Mondor Hospital, Department of Hematology and Cellular Therapy, Créteil, France; University Paris-Est Créteil (UPEC), Créteil, France.
Biol Blood Marrow Transplant ; 25(12): 2510-2513, 2019 12.
Article in En | MEDLINE | ID: mdl-31381996
ABSTRACT
Among 419 consecutive allogeneic hematopoietic cell transplant recipients, we observed 17 (4.0%) cases of toxoplasmosis at a median time of day 45 (range, 6 to 322) after transplant. Seven of these 17 cases occurred before day 30 after transplant. Because of the lack of PCR screening and trimethoprim-sulfamethoxazole prophylaxis before engraftment, the diagnosis of toxoplasmosis was late, and 5 of these 7 patients died. Analyzing these cases, early Toxoplasma blood PCR screening, starting from transplant, is crucial.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trimethoprim, Sulfamethoxazole Drug Combination / Toxoplasmosis / Hematopoietic Stem Cell Transplantation Type of study: Diagnostic_studies / Etiology_studies / Incidence_studies / Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: Biol Blood Marrow Transplant Journal subject: HEMATOLOGIA / TRANSPLANTE Year: 2019 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trimethoprim, Sulfamethoxazole Drug Combination / Toxoplasmosis / Hematopoietic Stem Cell Transplantation Type of study: Diagnostic_studies / Etiology_studies / Incidence_studies / Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: Biol Blood Marrow Transplant Journal subject: HEMATOLOGIA / TRANSPLANTE Year: 2019 Type: Article