Toxoplasmosis as an Early Complication of Allogeneic Hematopoietic Cell Transplantation.
Biol Blood Marrow Transplant
; 25(12): 2510-2513, 2019 12.
Article
in En
| MEDLINE
| ID: mdl-31381996
ABSTRACT
Among 419 consecutive allogeneic hematopoietic cell transplant recipients, we observed 17 (4.0%) cases of toxoplasmosis at a median time of day 45 (range, 6 to 322) after transplant. Seven of these 17 cases occurred before day 30 after transplant. Because of the lack of PCR screening and trimethoprim-sulfamethoxazole prophylaxis before engraftment, the diagnosis of toxoplasmosis was late, and 5 of these 7 patients died. Analyzing these cases, early Toxoplasma blood PCR screening, starting from transplant, is crucial.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Trimethoprim, Sulfamethoxazole Drug Combination
/
Toxoplasmosis
/
Hematopoietic Stem Cell Transplantation
Type of study:
Diagnostic_studies
/
Etiology_studies
/
Incidence_studies
/
Prognostic_studies
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Europa
Language:
En
Journal:
Biol Blood Marrow Transplant
Journal subject:
HEMATOLOGIA
/
TRANSPLANTE
Year:
2019
Type:
Article