Characterization of 3-[(Carboxymethyl)thio]picolinic Acid: A Novel Inhibitor of Phosphoenolpyruvate Carboxykinase.

Mcleod, Matthew J; Krismanich, Anthony P; Assoud, Abdeljalil; Dmitrienko, Gary I; Holyoak, Todd

Mcleod, Matthew J; Krismanich, Anthony P; Assoud, Abdeljalil; Dmitrienko, Gary I; Holyoak, Todd.

Biochemistry ; 58(37): 3918-3926, 2019 09 17.

Article in En | MEDLINE | ID: mdl-31461616

Subject(s)

Enzyme Inhibitors/chemistry; Intracellular Signaling Peptides and Proteins/antagonists & inhibitors; Intracellular Signaling Peptides and Proteins/chemistry; Phosphoenolpyruvate Carboxykinase (GTP)/antagonists & inhibitors; Phosphoenolpyruvate Carboxykinase (GTP)/chemistry; Picolinic Acids/chemistry; Animals; Crystallography/methods; Enzyme Inhibitors/pharmacology; Humans; Picolinic Acids/pharmacology; Protein Structure, Secondary; Rats

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphoenolpyruvate Carboxykinase (GTP) / Picolinic Acids / Intracellular Signaling Peptides and Proteins / Enzyme Inhibitors Limits: Animals / Humans Language: En Journal: Biochemistry Year: 2019 Type: Article

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