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CXCR4 upregulation is an indicator of sensitivity to B-cell receptor/PI3K blockade and a potential resistance mechanism in B-cell receptor-dependent diffuse large B-cell lymphomas.
Chen, Linfeng; Ouyang, Jing; Wienand, Kirsty; Bojarczuk, Kamil; Hao, Yansheng; Chapuy, Bjoern; Neuberg, Donna; Juszczynski, Przemyslaw; Lawton, Lee N; Rodig, Scott J; Monti, Stefano; Shipp, Margaret A.
Affiliation
  • Chen L; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Ouyang J; Current address: H3 Biomedicine, Cambridge, MA, USA.
  • Wienand K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Bojarczuk K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Hao Y; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Chapuy B; Current address: Department of Experimental Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.
  • Neuberg D; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Juszczynski P; Current Address: Department of Pathology, Mount Sinai Hospital, New York, NY, USA.
  • Lawton LN; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Rodig SJ; Current Address: Department of Hematology and Oncology, University Medical Center Göttingen, Göttingen, Germany.
  • Monti S; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, USA.
  • Shipp MA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Haematologica ; 105(5): 1361-1368, 2020 05.
Article in En | MEDLINE | ID: mdl-31471373
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphoma, Large B-Cell, Diffuse / Phosphatidylinositol 3-Kinases Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: Haematologica Year: 2020 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphoma, Large B-Cell, Diffuse / Phosphatidylinositol 3-Kinases Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: Haematologica Year: 2020 Type: Article Affiliation country: United States