Coexistence of TRH with other neuroactive substances in the rat central nervous system.
J Chem Neuroanat
; 1(5): 235-53, 1988.
Article
in En
| MEDLINE
| ID: mdl-3151546
ABSTRACT
Colocalization of thyrotropin-releasing hormone-like immunoreactivity with other neuroactive substances was examined immunohistochemically in colchicine-treated rat brains using double-staining or elution-restaining methods. Thyrotropin-releasing hormone-like immunoreactivity was shown to be located in the same neurons as 1. enkephalin-, gamma-amino butyric acid- and tyrosine hydroxylase-, but not somatostatin-like immunoreactivity in the glomerular layer of the olfactory bulb 2. oxytocin- and cholecystokinin-, but not vasopressin-like immunoreactivity in the supraoptic nucleus 3. cholecystokinin-like immunoreactivity in posterior pituitary 4. enkephalin-like immunoreactivity in the perifornical area of the hypothalamus and 5. neuropeptide Y- and neurotensin-like immunoreactivity in the periaqueductal central grey. These findings provide further examples of coexistence of thyrotropin-releasing hormone with classical neurotransmitters and/or peptides in the rat central nervous system.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Neuropeptides
/
Central Nervous System
/
Thyrotropin-Releasing Hormone
Limits:
Animals
Language:
En
Journal:
J Chem Neuroanat
Journal subject:
ANATOMIA
/
NEUROLOGIA
/
QUIMICA
Year:
1988
Type:
Article
Affiliation country:
Sweden