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A new prenylated coumarin and a new anthranilamide derivative from Evodia lepta.
Xie, Xing-Lin; Ye, Guo-Hua; Xue, Jun-Juan; Su, Tong; Tang, Gui-Hua; Li, Wei; Yin, Sheng.
Affiliation
  • Xie XL; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.
  • Ye GH; School of Chinese Medicine, Shandong College of Traditional Chinese Medicine, Yantai 264199, China.
  • Xue JJ; School of Chinese Medicine, Shandong College of Traditional Chinese Medicine, Yantai 264199, China.
  • Su T; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.
  • Tang GH; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.
  • Li W; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.
  • Yin S; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.
J Asian Nat Prod Res ; 22(5): 413-417, 2020 May.
Article in En | MEDLINE | ID: mdl-31565970
ABSTRACT
A new prenylated coumarin (1) and a new anthranilamide derivative (2) were isolated from the aerial parts of Evodia lepta. Compound 2 represents the first anthranilamide derivative from the Evodia genus. Their structures were elucidated by spectroscopic data analysis (MS, UV, IR, and NMR). Compound 1 exhibited certain inhibition on nitric oxide (NO) production induced by lipopolysaccharide (LPS) in RAW264.7 macrophages with an IC50 value of 37.96 ± 1.7 µM.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rutaceae / Evodia Language: En Journal: J Asian Nat Prod Res Journal subject: BOTANICA / QUIMICA Year: 2020 Type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rutaceae / Evodia Language: En Journal: J Asian Nat Prod Res Journal subject: BOTANICA / QUIMICA Year: 2020 Type: Article Affiliation country: China