Botox injection into the lower esophageal sphincter induces hiatal paralysis and gastroesophageal reflux.

Kumar, Dushyant; Zifan, Ali; Mittal, Ravinder K

Kumar, Dushyant; Zifan, Ali; Mittal, Ravinder K.

Affiliation

Kumar D; Division of Gastroenterology, Department of Medicine, University of California, San Diego, California.
Zifan A; Division of Gastroenterology, Department of Medicine, University of California, San Diego, California.
Mittal RK; Division of Gastroenterology, Department of Medicine, University of California, San Diego, California.

Am J Physiol Gastrointest Liver Physiol ; 318(1): G77-G83, 2020 01 01.

Article in En | MEDLINE | ID: mdl-31589467

Subject(s)

Acetylcholine Release Inhibitors/adverse effects; Botulinum Toxins, Type A/adverse effects; Diaphragm/drug effects; Esophageal Achalasia/drug therapy; Esophageal Sphincter, Lower/drug effects; Gastroesophageal Reflux/chemically induced; Muscle Contraction/drug effects; Respiratory Paralysis/chemically induced; Acetylcholine Release Inhibitors/administration & dosage; Adult; Aged; Botulinum Toxins, Type A/administration & dosage; Diaphragm/physiopathology; Esophageal Achalasia/diagnosis; Esophageal Achalasia/physiopathology; Esophageal Sphincter, Lower/physiopathology; Female; Gastroesophageal Reflux/diagnosis; Gastroesophageal Reflux/physiopathology; Humans; Injections, Intramuscular; Male; Middle Aged; Pressure; Respiratory Paralysis/diagnosis; Respiratory Paralysis/physiopathology; Risk Factors

Key words

Botox; crural diaphragm paralysis; esophageal motor disorders; esophagogastric junction; high-resolution manometry; lower esophageal sphincter

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Respiratory Paralysis / Diaphragm / Esophageal Achalasia / Gastroesophageal Reflux / Botulinum Toxins, Type A / Esophageal Sphincter, Lower / Acetylcholine Release Inhibitors / Muscle Contraction Type of study: Diagnostic_studies / Etiology_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Am J Physiol Gastrointest Liver Physiol Journal subject: FISIOLOGIA / GASTROENTEROLOGIA Year: 2020 Type: Article

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