Developing Broad-Spectrum Antivirals Using Porcine and Rhesus Macaque Models.

Qiu, Xueer; Taft, Justin; Bogunovic, Dusan

Qiu, Xueer; Taft, Justin; Bogunovic, Dusan.

Affiliation

Qiu X; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Taft J; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Bogunovic D; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

J Infect Dis ; 221(6): 890-894, 2020 03 02.

Article in En | MEDLINE | ID: mdl-31637432

Subject(s)

Antiviral Agents/pharmacology; Animals; Cells, Cultured; Cytokines/metabolism; Gene Deletion; Gene Expression Regulation, Enzymologic/drug effects; Humans; Macaca mulatta; Phylogeny; Species Specificity; Swine; Ubiquitin Thiolesterase/genetics; Ubiquitin Thiolesterase/metabolism; Ubiquitins/metabolism

Key words

ISG15 deficiency; USP18; broad-spectrum antiviral

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents Limits: Animals / Humans Language: En Journal: J Infect Dis Year: 2020 Type: Article Affiliation country: United States

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