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Small molecule screening identifies inhibitors of the Epstein-Barr virus deubiquitinating enzyme, BPLF1.
Atkins, Sage L; Motaib, Safiyyah; Wiser, Laura C; Hopcraft, Sharon E; Hardy, Paul B; Shackelford, Julia; Foote, Peter; Wade, Ashley H; Damania, Blossom; Pagano, Joseph S; Pearce, Kenneth H; Whitehurst, Christopher B.
Affiliation
  • Atkins SL; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Motaib S; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Wiser LC; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Hopcraft SE; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Hardy PB; Eshelman School of Pharmacy, Center for Integrative Biology and Drug Discovery, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Shackelford J; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Foote P; Life Sensors Inc, Malvern, PA, USA.
  • Wade AH; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Damania B; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Pagano JS; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Pearce KH; Eshelman School of Pharmacy, Center for Integrative Biology and Drug Discovery, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Whitehurst CB; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: cbwhiteh@med.unc.edu.
Antiviral Res ; 173: 104649, 2020 01.
Article in En | MEDLINE | ID: mdl-31711927
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Herpesvirus 4, Human / Drug Evaluation, Preclinical / Viral Regulatory and Accessory Proteins / Deubiquitinating Enzymes Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Humans Language: En Journal: Antiviral Res Year: 2020 Type: Article Affiliation country: United States
Fulltext
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Herpesvirus 4, Human / Drug Evaluation, Preclinical / Viral Regulatory and Accessory Proteins / Deubiquitinating Enzymes Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Humans Language: En Journal: Antiviral Res Year: 2020 Type: Article Affiliation country: United States