Validation of a novel ultrasound Doppler monitoring device (earlybird) for detection of microvascular circulatory changes.
Clin Hemorheol Microcirc
; 74(4): 429-440, 2020.
Article
in En
| MEDLINE
| ID: mdl-31743988
ABSTRACT
OBJECTIVE:
In this proof-of-concept study we aim to validate a novel ultrasound Doppler monitoring device for evaluating microcirculation (earlybird) against LDF and pulsed Doppler.METHODS:
In ten healthy subjects, we measured microcirculatory function at rest and during different autonomic tests (forced respiration, isometric exercise, Valsalva maneuver and cold pressor). Earlybird, LDF and pulsed Doppler were recorded simultaneously. We performed a ZNCC to determine correlation.RESULTS:
The curves for earlybird and LDF or pulsed Doppler correlates visually well. Overall median ZNCC 0.87 (interquartile range 0.77 -0.91) between the LDF and earlybird measurements, and 0.90 (0.82 - 0.95) for pulsed Doppler and earlybird. Median ZNCC for baseline and each provocation test for earlybird against LDF and pulsed Doppler were calculated; baseline LDF 0.87 (0.73 - 0.97) pulsed Doppler 0.91 (0.81 - 0.94), forced respiration LDF 0.87 (0.28 - 0.90) pulsed Doppler 0.90 (0.85 - 0.96), isometric exercise LDF 0.82 (0.59 - 0.90) pulsed Doppler 0.87 (0.68 - 0.94), Valsalva maneuver LDF 0.88 (0.82 - 0.91) pulsed Doppler 0.94 (0.92 - 0.97) and cold pressor LDF 0.90 (0.85 - 0.95) pulsed Doppler 0.89 (0.65 - 0.94).CONCLUSION:
Earlybird records vasoconstrictions in healthy subjects as well as LDF and pulsed Doppler.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Regional Blood Flow
/
Ultrasonography
/
Laser-Doppler Flowmetry
/
Microcirculation
Type of study:
Diagnostic_studies
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Clin Hemorheol Microcirc
Journal subject:
ANGIOLOGIA
/
HEMATOLOGIA
Year:
2020
Type:
Article
Affiliation country:
Norway