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Fatty acid synthase inhibitor orlistat impairs cell growth and down-regulates PD-L1 expression of a human T-cell leukemia line.
Cioccoloni, Giorgia; Aquino, Angelo; Notarnicola, Maria; Caruso, Maria Gabriella; Bonmassar, Enzo; Zonfrillo, Manuela; Caporali, Simona; Faraoni, Isabella; Villivà, Cristina; Fuggetta, Maria Pia; Franzese, Ornella.
Affiliation
  • Cioccoloni G; Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
  • Aquino A; Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
  • Notarnicola M; Laboratory of Nutritional Biochemistry, National Institute for Digestive Diseases S. de Bellis, Bari, Italy.
  • Caruso MG; Laboratory of Nutritional Biochemistry, National Institute for Digestive Diseases S. de Bellis, Bari, Italy.
  • Bonmassar E; Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
  • Zonfrillo M; Institute of Translational Pharmacology, National Council of Research, Rome, Italy.
  • Caporali S; Institute of Translational Pharmacology, National Council of Research, Rome, Italy.
  • Faraoni I; Laboratory of Molecular Oncology, IDI-IRCCS Rome, Rome, Italy.
  • Villivà C; Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
  • Fuggetta MP; Institute of Translational Pharmacology, National Council of Research, Rome, Italy.
  • Franzese O; Institute of Translational Pharmacology, National Council of Research, Rome, Italy.
J Chemother ; 32(1): 30-40, 2020 Feb.
Article in En | MEDLINE | ID: mdl-31775585
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, T-Cell / Enzyme Inhibitors / Fatty Acid Synthase, Type I / B7-H1 Antigen / Orlistat Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Chemother Journal subject: ANTINEOPLASICOS / TERAPIA POR MEDICAMENTOS Year: 2020 Type: Article Affiliation country: Italy
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, T-Cell / Enzyme Inhibitors / Fatty Acid Synthase, Type I / B7-H1 Antigen / Orlistat Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Chemother Journal subject: ANTINEOPLASICOS / TERAPIA POR MEDICAMENTOS Year: 2020 Type: Article Affiliation country: Italy