A rare case of non-small cell lung cancer choroidal metastasis responding to ALK tyrosine kinase inhibitors.
Anticancer Drugs
; 31(1): 90-94, 2020 01.
Article
in En
| MEDLINE
| ID: mdl-31804301
ABSTRACT
Choroidal localization from non-small cell lung cancer is rare and when it occurs may cause visual alterations. Targeted therapy against actionable gene mutations represents the standard of care in advanced non-small cell lung cancer. We report the case of a 53-year-old woman affected by metastatic anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancer who received ALK tyrosine kinase inhibitors, from January 2017. The patient had a complete response of choroidal metastasis after therapy with ALK tyrosine kinase inhibitors. She recovered a complete visus and actually she still continue therapy with alectinib. The patient had a complete recovery of visus in addiction to a long response on treatment.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Antineoplastic Combined Chemotherapy Protocols
/
Choroid Neoplasms
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Carcinoma, Non-Small-Cell Lung
/
Lung Neoplasms
Limits:
Female
/
Humans
/
Middle aged
Language:
En
Journal:
Anticancer Drugs
Journal subject:
ANTINEOPLASICOS
Year:
2020
Type:
Article