Göttingen Minipig is not a Suitable Animal Model for <i>in Vivo</i> Testing of Tissue-Engineered Corneal Endothelial Cell-Carrier Sheets and for Endothelial Keratoplasty.

Telinius, Niklas; Spinozzi, Daniele; Rasic, Dusan; Dapena, Isabel; Baandrup, Ulrik; Miron, Alina; Oellerich, Silke; Hjortdal, Jesper

Göttingen Minipig is not a Suitable Animal Model for in Vivo Testing of Tissue-Engineered Corneal Endothelial Cell-Carrier Sheets and for Endothelial Keratoplasty.

Telinius, Niklas; Spinozzi, Daniele; Rasic, Dusan; Dapena, Isabel; Baandrup, Ulrik; Miron, Alina; Oellerich, Silke; Hjortdal, Jesper.

Affiliation

Telinius N; Department of Ophthalmology, Aarhus University Hospital , Aarhus, Denmark.
Spinozzi D; Netherlands Institute for Innovative Ocular Surgery , Rotterdam, The Netherlands.
Rasic D; Center for Clinical Research, Regional Hospital North Jutland, Hjørring, Denmark and Aalborg University , Aalborg, Denmark.
Dapena I; Netherlands Institute for Innovative Ocular Surgery , Rotterdam, The Netherlands.
Baandrup U; Center for Clinical Research, Regional Hospital North Jutland, Hjørring, Denmark and Aalborg University , Aalborg, Denmark.
Miron A; Netherlands Institute for Innovative Ocular Surgery , Rotterdam, The Netherlands.
Oellerich S; Netherlands Institute for Innovative Ocular Surgery , Rotterdam, The Netherlands.
Hjortdal J; Department of Ophthalmology, Aarhus University Hospital , Aarhus, Denmark.

Curr Eye Res ; 45(8): 945-949, 2020 08.

Article in En | MEDLINE | ID: mdl-31851850

Subject(s)

Corneal Transplantation/methods; Disease Models, Animal; Endothelium, Corneal/transplantation; Tissue Engineering/methods; Animals; Anterior Chamber/pathology; Cell Culture Techniques; Cell- and Tissue-Based Therapy/methods; Corneal Edema/diagnosis; Corneal Edema/etiology; Debridement; Denmark; Endothelium, Corneal/cytology; Endothelium, Corneal/diagnostic imaging; Feasibility Studies; Fibrosis; Lens Capsule, Crystalline/cytology; Slit Lamp Microscopy; Swine; Swine, Miniature; Tomography, Optical Coherence

Key words

Endothelial cell transplantation; animal models; cell carriers; retrocorneal membrane

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endothelium, Corneal / Corneal Transplantation / Tissue Engineering / Disease Models, Animal Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies Limits: Animals Country/Region as subject: Europa Language: En Journal: Curr Eye Res Year: 2020 Type: Article Affiliation country: Denmark

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