Your browser doesn't support javascript.
loading
Comprehensive engineering of the tarantula venom peptide huwentoxin-IV to inhibit the human voltage-gated sodium channel hNav1.7.
Neff, Robert A; Flinspach, Mack; Gibbs, Alan; Shih, Amy Y; Minassian, Natali A; Liu, Yi; Fellows, Ross; Libiger, Ondrej; Young, Stephanie; Pennington, Michael W; Hunter, Michael J; Wickenden, Alan D.
Affiliation
  • Neff RA; Neuroscience Discovery, Janssen Research and Development, LLC, San Diego, California 92121 rneff@its.jnj.com.
  • Flinspach M; Biologics Research, Janssen Research and Development, LLC, San Diego, California 92121.
  • Gibbs A; Structural Biology, Janssen Research and Development, LLC, Spring House, Pennsylvania 19477.
  • Shih AY; Discovery Chemistry-Computational Chemistry, Janssen Research and Development, LLC, San Diego, California 92121.
  • Minassian NA; Neuroscience Discovery, Janssen Research and Development, LLC, San Diego, California 92121.
  • Liu Y; Neuroscience Discovery, Janssen Research and Development, LLC, San Diego, California 92121.
  • Fellows R; Biologics Research, Janssen Research and Development, LLC, San Diego, California 92121.
  • Libiger O; Translational Medicine and Early Development Statistics, Janssen Research and Development, LLC, San Diego, California 92121.
  • Young S; Translational Medicine and Early Development Statistics, Janssen Research and Development, LLC, San Diego, California 92121.
  • Pennington MW; Peptides International, Inc., Louisville, Kentucky 40299.
  • Hunter MJ; Biologics Research, Janssen Research and Development, LLC, San Diego, California 92121.
  • Wickenden AD; Molecular and Cellular Pharmacology, Janssen Research and Development, LLC, San Diego, California 92121.
J Biol Chem ; 295(5): 1315-1327, 2020 01 31.
Article in En | MEDLINE | ID: mdl-31871053
Subject(s)
Key words
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spider Venoms / NAV1.7 Voltage-Gated Sodium Channel / Voltage-Gated Sodium Channel Blockers / Analgesics Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Biol Chem Year: 2020 Type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spider Venoms / NAV1.7 Voltage-Gated Sodium Channel / Voltage-Gated Sodium Channel Blockers / Analgesics Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Biol Chem Year: 2020 Type: Article