Alterations of thyroidal status in brain regions and hypothalamo-pituitary-blood-thyroid-axis associated with dopaminergic depletion in substantia nigra and ROS formation in different brain regions after MPTP treatment in adult male mice.

Sinha, Priyobrata; Chakrabarti, Nilkanta; Ghosh, Nabanita; Mitra, Soham; Dalui, Shauryabrota; Bhattacharyya, Arindam

Sinha, Priyobrata; Chakrabarti, Nilkanta; Ghosh, Nabanita; Mitra, Soham; Dalui, Shauryabrota; Bhattacharyya, Arindam.

Affiliation

Sinha P; Immunology Lab, Department of Zoology, University of Calcutta, 35, Ballygunge Circular Road, Kolkata 700019, India; Department of Physiology, University of Calcutta, 92, Acharya Prafulla Chandra Road, Kolkata 700009, India.
Chakrabarti N; Department of Physiology, University of Calcutta, 92, Acharya Prafulla Chandra Road, Kolkata 700009, India; Centres with Potential for Excellence in Particular Areas (CPEPA, UGC), Centre for "Electrophysiology & Neuroimaging Studies Including Mathematical Modeling" India. Electronic address: ncp
Ghosh N; Immunology Lab, Department of Zoology, University of Calcutta, 35, Ballygunge Circular Road, Kolkata 700019, India.
Mitra S; Immunology Lab, Department of Zoology, University of Calcutta, 35, Ballygunge Circular Road, Kolkata 700019, India.
Dalui S; Immunology Lab, Department of Zoology, University of Calcutta, 35, Ballygunge Circular Road, Kolkata 700019, India.
Bhattacharyya A; Immunology Lab, Department of Zoology, University of Calcutta, 35, Ballygunge Circular Road, Kolkata 700019, India. Electronic address: arindam19@yahoo.com.

Brain Res Bull ; 156: 131-140, 2020 03.

Article in En | MEDLINE | ID: mdl-31891753

Subject(s)

Brain/drug effects; Dopaminergic Neurons/metabolism; Thyroid Gland/drug effects; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine/pharmacology; Animals; Brain/metabolism; Cerebral Cortex/metabolism; Dopaminergic Neurons/drug effects; Hypothalamus/metabolism; Male; Mice; Reactive Oxygen Species/metabolism; Substantia Nigra/metabolism; Thyroid Gland/metabolism; Thyroid Hormones/blood; Thyrotropin/blood; Thyroxine/blood

Key words

Different brain regions; Dopaminergic neurons; Hypothalamo-pituitary-blood-thyroid axis; MPTP; ROS; Thyroidal status

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thyroid Gland / Brain / Dopaminergic Neurons Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Brain Res Bull Year: 2020 Type: Article Affiliation country: India

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