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A randomised phase II trial of hydroxychloroquine and imatinib versus imatinib alone for patients with chronic myeloid leukaemia in major cytogenetic response with residual disease.
Horne, G A; Stobo, J; Kelly, C; Mukhopadhyay, A; Latif, A L; Dixon-Hughes, J; McMahon, L; Cony-Makhoul, P; Byrne, J; Smith, G; Koschmieder, S; BrÜmmendorf, T H; Schafhausen, P; Gallipoli, P; Thomson, F; Cong, W; Clark, R E; Milojkovic, D; Helgason, G V; Foroni, L; Nicolini, F E; Holyoake, T L; Copland, M.
Affiliation
  • Horne GA; Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.
  • Stobo J; Cancer Research UK Clinical Trials Unit, University of Glasgow, Glasgow, UK.
  • Kelly C; Cancer Research UK Clinical Trials Unit, University of Glasgow, Glasgow, UK.
  • Mukhopadhyay A; Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.
  • Latif AL; Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.
  • Dixon-Hughes J; Cancer Research UK Clinical Trials Unit, University of Glasgow, Glasgow, UK.
  • McMahon L; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.
  • Cony-Makhoul P; Haematology department, CH Annecy-Genevois, Pringy, France.
  • Byrne J; Department of Haematology, Nottingham City Hospital, Nottingham, UK.
  • Smith G; Department of Haematology, St James's University Hospital, Leeds, UK.
  • Koschmieder S; Department of Medicine (Hematology Oncology, Hemostaseology, and Stem Cell Transplantation), Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
  • BrÜmmendorf TH; Department of Medicine (Hematology Oncology, Hemostaseology, and Stem Cell Transplantation), Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
  • Schafhausen P; Department of Internal Medicine, University Medical Center Hamburg, Hamburg, Germany.
  • Gallipoli P; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
  • Thomson F; Experimental therapeutics, Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.
  • Cong W; Experimental therapeutics, Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.
  • Clark RE; Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK.
  • Milojkovic D; Department of Haematology, Hammersmith Hospital, London, UK.
  • Helgason GV; Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.
  • Foroni L; Department of Haematology, Imperial College London, London, UK.
  • Nicolini FE; Hématologie Clinique and INSERM U1052, CRCL, Centre Léon Bérard, Lyon, France.
  • Holyoake TL; Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.
  • Copland M; Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK. Mhairi.Copland@glasgow.ac.uk.
Leukemia ; 34(7): 1775-1786, 2020 07.
Article in En | MEDLINE | ID: mdl-31925317
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Antineoplastic Combined Chemotherapy Protocols / Fusion Proteins, bcr-abl / Cytogenetic Analysis Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2020 Type: Article Affiliation country: United kingdom
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Antineoplastic Combined Chemotherapy Protocols / Fusion Proteins, bcr-abl / Cytogenetic Analysis Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2020 Type: Article Affiliation country: United kingdom