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Characterization of breakthrough hemolysis events observed in the phase 3 randomized studies of ravulizumab versus eculizumab in adults with paroxysmal nocturnal hemoglobinuria.
Brodsky, Robert A; Peffault de Latour, Régis; Rottinghaus, Scott T; Röth, Alexander; Risitano, Antonio M; Weitz, Ilene C; Hillmen, Peter; Maciejewski, Jaroslaw P; Szer, Jeff; Lee, Jong Wook; Kulasekararaj, Austin G; Volles, Lori; Damokosh, Andrew I; Ortiz, Stephan; Shafner, Lori; Liu, Peng; Hill, Anita; Schrezenmeier, Hubert.
Affiliation
  • Brodsky RA; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Peffault de Latour R; Université Paris Diderot and Hôpital Saint-Louis AP-HP, Paris.
  • Rottinghaus ST; Alexion Pharmaceuticals, Inc., Boston, MA.
  • Röth A; Department of Hematology, University Hospital Essen, University of Duisburg-Essen, Essen.
  • Risitano AM; Department of Clinical Medicine and Surgery, Federico II University of Naples, Naples.
  • Weitz IC; Jane Anne Nohl Division of Hematology, Keck-USC School of Medicine, Los Angeles, CA, USA.
  • Hillmen P; Department of Haematology, St James's University Hospital, Leeds.
  • Maciejewski JP; Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.
  • Szer J; Clinical Haematology, Royal Melbourne Hospital, Melbourne.
  • Lee JW; The Catholic University of Korea, College of Medicine, Seoul.
  • Kulasekararaj AG; Department of Haematological Medicine, King College Hospital, London.
  • Volles L; Alexion Pharmaceuticals, Inc., Boston, MA.
  • Damokosh AI; Alexion Pharmaceuticals, Inc., Boston, MA.
  • Ortiz S; Alexion Pharmaceuticals, Inc., Boston, MA.
  • Shafner L; Alexion Pharmaceuticals, Inc., Boston, MA, USA.
  • Liu P; Alexion Pharmaceuticals, Inc., Boston, MA.
  • Hill A; Department of Haematology, St James's University Hospital, Leeds.
  • Schrezenmeier H; German Red Cross Blood Transfusion Service, Baden-Wurttemberg-Hessen and University Hospital Ulm.
Haematologica ; 106(1): 230-237, 2021 01 01.
Article in En | MEDLINE | ID: mdl-31949012
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hemoglobinuria, Paroxysmal Type of study: Clinical_trials Limits: Adult / Humans Language: En Journal: Haematologica Year: 2021 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hemoglobinuria, Paroxysmal Type of study: Clinical_trials Limits: Adult / Humans Language: En Journal: Haematologica Year: 2021 Type: Article Affiliation country: United States