Synergistic effects of vorinostat (SAHA) and azoles against Aspergillus species and their biofilms.

Tu, Bo; Yin, Gendi; Li, Hui

Tu, Bo; Yin, Gendi; Li, Hui.

Affiliation

Tu B; Department of Otorhinolaryngology and Head Neck Surgery, the First Affiliated Hospital of Jinan University, Guangzhou, 510630, Guangdong, People's Republic of China.
Yin G; Department of Otolaryngology Head Neck Surgery, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, Guangdong, People's Republic of China.
Li H; Department of Otorhinolaryngology and Head Neck Surgery, the First Affiliated Hospital of Jinan University, Guangzhou, 510630, Guangdong, People's Republic of China. huilidoct@163.com.

BMC Microbiol ; 20(1): 28, 2020 02 07.

Article in En | MEDLINE | ID: mdl-32028887

Subject(s)

Aspergillus/physiology; Azoles/pharmacology; Biofilms/drug effects; Plankton/microbiology; Vorinostat/pharmacology; ATP Binding Cassette Transporter, Subfamily B/genetics; ATP Binding Cassette Transporter, Subfamily B, Member 1/genetics; Aspergillus/drug effects; Aspergillus/isolation & purification; Drug Synergism; Gene Expression Regulation/drug effects; HSP90 Heat-Shock Proteins/genetics; Itraconazole/pharmacology; Microbial Sensitivity Tests; Plankton/drug effects; Plankton/genetics; Triazoles/pharmacology; Voriconazole/pharmacology; ATP-Binding Cassette Sub-Family B Member 4

Key words

Antifungals; Aspergillus; Biofilm; Combination; HSP90; SAHA

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plankton / Aspergillus / Azoles / Biofilms / Vorinostat Language: En Journal: BMC Microbiol Journal subject: MICROBIOLOGIA Year: 2020 Type: Article

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