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Nicotinamide activates latent HIV-1 ex vivo in ART suppressed individuals, revealing higher potency than the association of two methyltransferase inhibitors, chaetocin and BIX01294.
Samer, Sadia; Arif, Muhammad Shoaib; Giron, Leila Bertoni; Zukurov, Jean Paulo Lopes; Hunter, James; Santillo, Bruna Teresa; Namiyama, Gislene; Galinskas, Juliana; Komninakis, Shirley Vasconcelos; Oshiro, Telma Miyuki; Sucupira, Maria Cecilia; Janini, Luiz Mario; Diaz, Ricardo Sobhie.
Affiliation
  • Samer S; Yerkes National Primate Research Center, Emory University, Atlanta, Georgia.
  • Arif MS; Department of Cell and Developmental Biology, Feinberg School of Medicine, Northwestern University, Chicago, USA. Electronic address: shoaib.arif@hotmail.com.
  • Giron LB; Wistar Institute, Philadelphia, USA.
  • Zukurov JPL; Department of Microbiology, Immunology and Parasitology, Federal University of São Paulo, São Paulo, SP, Brazil.
  • Hunter J; Department of Medicine, Federal University of Sao Paulo, São Paulo, SP, Brazil.
  • Santillo BT; Department of Dermatology, University of Sao Paulo, São Paulo, SP, Brazil.
  • Namiyama G; Department of Electron Microscopy, Institute of Adolfo Lutz, São Paulo, SP, Brazil.
  • Galinskas J; Department of Medicine, Federal University of Sao Paulo, São Paulo, SP, Brazil.
  • Komninakis SV; Department of Medicine, Federal University of Sao Paulo, São Paulo, SP, Brazil.
  • Oshiro TM; Department of Dermatology, University of Sao Paulo, São Paulo, SP, Brazil.
  • Sucupira MC; Department of Medicine, Federal University of Sao Paulo, São Paulo, SP, Brazil.
  • Janini LM; Department of Microbiology, Immunology and Parasitology, Federal University of São Paulo, São Paulo, SP, Brazil.
  • Diaz RS; Department of Medicine, Federal University of Sao Paulo, São Paulo, SP, Brazil. Electronic address: rsdiaz@catg.com.br.
Braz J Infect Dis ; 24(2): 150-159, 2020.
Article in En | MEDLINE | ID: mdl-32105620
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quinazolines / Azepines / Virus Activation / HIV Infections / HIV-1 / Niacinamide / Methyltransferases Type of study: Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Braz J Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2020 Type: Article Affiliation country: Georgia
Fulltext
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quinazolines / Azepines / Virus Activation / HIV Infections / HIV-1 / Niacinamide / Methyltransferases Type of study: Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Braz J Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2020 Type: Article Affiliation country: Georgia