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Mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway.
Guo, Xiaoyan; Aviles, Giovanni; Liu, Yi; Tian, Ruilin; Unger, Bret A; Lin, Yu-Hsiu T; Wiita, Arun P; Xu, Ke; Correia, M Almira; Kampmann, Martin.
Affiliation
  • Guo X; Institute for Neurodegenerative Diseases, University of California, San Francisco, San Francisco, CA, USA.
  • Aviles G; Chan Zuckerberg Biohub, San Francisco, CA, USA.
  • Liu Y; Institute for Neurodegenerative Diseases, University of California, San Francisco, San Francisco, CA, USA.
  • Tian R; Chan Zuckerberg Biohub, San Francisco, CA, USA.
  • Unger BA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA.
  • Lin YT; Institute for Neurodegenerative Diseases, University of California, San Francisco, San Francisco, CA, USA.
  • Wiita AP; Chan Zuckerberg Biohub, San Francisco, CA, USA.
  • Xu K; Biophysics Graduate Program, University of California, San Francisco, San Francisco, CA, USA.
  • Correia MA; Chan Zuckerberg Biohub, San Francisco, CA, USA.
  • Kampmann M; Department of Chemistry, University of California, Berkeley, Berkeley, CA, USA.
Nature ; 579(7799): 427-432, 2020 03.
Article in En | MEDLINE | ID: mdl-32132707
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stress, Physiological / Metalloendopeptidases / EIF-2 Kinase / Cytosol / Mitochondrial Proteins / Mitochondria Type of study: Prognostic_studies Limits: Humans / Male Language: En Journal: Nature Year: 2020 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stress, Physiological / Metalloendopeptidases / EIF-2 Kinase / Cytosol / Mitochondrial Proteins / Mitochondria Type of study: Prognostic_studies Limits: Humans / Male Language: En Journal: Nature Year: 2020 Type: Article Affiliation country: United States