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Neutralizing antibody VRC01 failed to select for HIV-1 mutations upon viral rebound.
Cale, Evan M; Bai, Hongjun; Bose, Meera; Messina, Michael A; Colby, Donn J; Sanders-Buell, Eric; Dearlove, Bethany; Li, Yifan; Engeman, Emily; Silas, Daniel; O'Sullivan, Anne Marie; Mann, Brendan; Pinyakorn, Suteeraporn; Intasan, Jintana; Benjapornpong, Khunthalee; Sacdalan, Carlo; Kroon, Eugène; Phanuphak, Nittaya; Gramzinski, Robert; Vasan, Sandhya; Robb, Merlin L; Michael, Nelson L; Lynch, Rebecca M; Bailer, Robert T; Pagliuzza, Amélie; Chomont, Nicolas; Pegu, Amarendra; Doria-Rose, Nicole A; Trautmann, Lydie; Crowell, Trevor A; Mascola, John R; Ananworanich, Jintanat; Tovanabutra, Sodsai; Rolland, Morgane.
Affiliation
  • Cale EM; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA.
  • Bai H; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
  • Bose M; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, Maryland, USA.
  • Messina MA; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
  • Colby DJ; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, Maryland, USA.
  • Sanders-Buell E; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA.
  • Dearlove B; SEARCH, Thai Red Cross Research Center, Bangkok, Thailand.
  • Li Y; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
  • Engeman E; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, Maryland, USA.
  • Silas D; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
  • O'Sullivan AM; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, Maryland, USA.
  • Mann B; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
  • Pinyakorn S; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, Maryland, USA.
  • Intasan J; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
  • Benjapornpong K; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, Maryland, USA.
  • Sacdalan C; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
  • Kroon E; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, Maryland, USA.
  • Phanuphak N; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
  • Gramzinski R; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, Maryland, USA.
  • Vasan S; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
  • Robb ML; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, Maryland, USA.
  • Michael NL; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
  • Lynch RM; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, Maryland, USA.
  • Bailer RT; SEARCH, Thai Red Cross Research Center, Bangkok, Thailand.
  • Pagliuzza A; SEARCH, Thai Red Cross Research Center, Bangkok, Thailand.
  • Chomont N; SEARCH, Thai Red Cross Research Center, Bangkok, Thailand.
  • Pegu A; SEARCH, Thai Red Cross Research Center, Bangkok, Thailand.
  • Doria-Rose NA; SEARCH, Thai Red Cross Research Center, Bangkok, Thailand.
  • Trautmann L; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
  • Crowell TA; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
  • Mascola JR; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, Maryland, USA.
  • Ananworanich J; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
  • Tovanabutra S; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, Maryland, USA.
  • Rolland M; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
J Clin Invest ; 130(6): 3299-3304, 2020 06 01.
Article in En | MEDLINE | ID: mdl-32182219
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Antibodies / HIV Infections / HIV-1 / Env Gene Products, Human Immunodeficiency Virus / Antibodies, Neutralizing / Mutation / Epitopes Type of study: Clinical_trials Limits: Female / Humans / Male Language: En Journal: J Clin Invest Year: 2020 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Antibodies / HIV Infections / HIV-1 / Env Gene Products, Human Immunodeficiency Virus / Antibodies, Neutralizing / Mutation / Epitopes Type of study: Clinical_trials Limits: Female / Humans / Male Language: En Journal: J Clin Invest Year: 2020 Type: Article Affiliation country: United States