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Aryl-4,5-dihydro-1H-pyrazole-1-carboxamide Derivatives Bearing a Sulfonamide Moiety Show Single-digit Nanomolar-to-Subnanomolar Inhibition Constants against the Tumor-associated Human Carbonic Anhydrases IX and XII.
Hargunani, Priya; Tadge, Nikhil; Ceruso, Mariangela; Leitans, Janis; Kazaks, Andris; Tars, Kaspars; Gratteri, Paola; Supuran, Claudiu T; Nocentini, Alessio; Toraskar, Mrunmayee P.
Affiliation
  • Hargunani P; Bharati Vidyapeeth's College of Pharmacy, Navi Mumbai 400 614, India.
  • Tadge N; Bharati Vidyapeeth's College of Pharmacy, Navi Mumbai 400 614, India.
  • Ceruso M; Neurofarba Dept., Section of Pharmaceutical and Nutraceutical Sciences, Universitá degli Studi di Firenze, Via U. Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.
  • Leitans J; Latvian Biomedical Research and Study Center, Ratsupites 1, LV-1067 Riga, Latvia.
  • Kazaks A; Latvian Biomedical Research and Study Center, Ratsupites 1, LV-1067 Riga, Latvia.
  • Tars K; Latvian Biomedical Research and Study Center, Ratsupites 1, LV-1067 Riga, Latvia.
  • Gratteri P; Neurofarba Dept., Section of Pharmaceutical and Nutraceutical Sciences, Universitá degli Studi di Firenze, Via U. Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.
  • Supuran CT; Neurofarba Dept., Section of Pharmaceutical and Nutraceutical Sciences, Universitá degli Studi di Firenze, Via U. Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.
  • Nocentini A; Neurofarba Dept., Section of Pharmaceutical and Nutraceutical Sciences, Universitá degli Studi di Firenze, Via U. Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.
  • Toraskar MP; Bharati Vidyapeeth's College of Pharmacy, Navi Mumbai 400 614, India.
Int J Mol Sci ; 21(7)2020 Apr 09.
Article in En | MEDLINE | ID: mdl-32283813
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Carbonic Anhydrase Inhibitors / Carbonic Anhydrases / Antineoplastic Agents Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Int J Mol Sci Year: 2020 Type: Article Affiliation country: India
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Carbonic Anhydrase Inhibitors / Carbonic Anhydrases / Antineoplastic Agents Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Int J Mol Sci Year: 2020 Type: Article Affiliation country: India