An Efficient Synthetic Approach Towards Benzo[<i>b</i>]pyrano[2,3-<i>e</i>][1,4]diazepines, and Their Cytotoxic Activity.

El Azab, Islam H; Elkanzi, Nadia A A

An Efficient Synthetic Approach Towards Benzo[b]pyrano[2,3-e][1,4]diazepines, and Their Cytotoxic Activity.

El Azab, Islam H; Elkanzi, Nadia A A.

Affiliation

El Azab IH; Chemistry Department, Faculty of Science, Taif University, Al-Haweiah, P.O. Box 888, Taif 21974, Saudi Arabia.
Elkanzi NAA; On leave from Chemistry Department, Faculty of Science, Aswan University, Aswan, P.O. Box, Aswan 81528, Egypt.

Molecules ; 25(9)2020 Apr 28.

Article in En | MEDLINE | ID: mdl-32354014

Subject(s)

Benzodiazepines/chemical synthesis; Benzodiazepines/pharmacology; Chemistry, Pharmaceutical/methods; Drug Design; Drug Screening Assays, Antitumor; Antineoplastic Agents/chemical synthesis; Antineoplastic Agents/pharmacology; Cell Line, Tumor; Chemistry Techniques, Synthetic; Doxorubicin/pharmacology; HCT116 Cells; Humans; Inhibitory Concentration 50; MCF-7 Cells; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Spectrophotometry, Infrared

Key words

N-heterocycles; benzodiazepine; cyclocondensation reaction; cytotoxic activity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzodiazepines / Drug Screening Assays, Antitumor / Drug Design / Chemistry, Pharmaceutical Limits: Humans Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2020 Type: Article Affiliation country: Saudi Arabia

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