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Predictive Utility of Polygenic Risk Scores for Coronary Heart Disease in Three Major Racial and Ethnic Groups.
Dikilitas, Ozan; Schaid, Daniel J; Kosel, Matthew L; Carroll, Robert J; Chute, Christopher G; Denny, Joshua A; Fedotov, Alex; Feng, QiPing; Hakonarson, Hakon; Jarvik, Gail P; Lee, Ming Ta Michael; Pacheco, Jennifer A; Rowley, Robb; Sleiman, Patrick M; Stein, C Michael; Sturm, Amy C; Wei, Wei-Qi; Wiesner, Georgia L; Williams, Marc S; Zhang, Yanfei; Manolio, Teri A; Kullo, Iftikhar J.
Affiliation
  • Dikilitas O; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55905, USA.
  • Schaid DJ; Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.
  • Kosel ML; Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.
  • Carroll RJ; Department of Biomedical Informatics, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37212, USA.
  • Chute CG; Schools of Medicine, Public Health, and Nursing, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Denny JA; Department of Biomedical Informatics, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37212, USA.
  • Fedotov A; Irving Institute for Clinical and Translational Research, Columbia University Medical Center, New York, NY 10032, USA.
  • Feng Q; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37212, USA.
  • Hakonarson H; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Jarvik GP; Department of Medicine, University of Washington, Seattle, WA 98195, USA.
  • Lee MTM; Geisinger, Danville, PA 17822, USA.
  • Pacheco JA; Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Rowley R; National Human Genome Research Institute, Bethesda, MD 20892, USA.
  • Sleiman PM; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Stein CM; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37212, USA.
  • Sturm AC; Geisinger, Danville, PA 17822, USA.
  • Wei WQ; Department of Biomedical Informatics, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37212, USA.
  • Wiesner GL; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37212, USA.
  • Williams MS; Geisinger, Danville, PA 17822, USA.
  • Zhang Y; Geisinger, Danville, PA 17822, USA.
  • Manolio TA; National Human Genome Research Institute, Bethesda, MD 20892, USA.
  • Kullo IJ; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55905, USA. Electronic address: kullo.iftikhar@mayo.edu.
Am J Hum Genet ; 106(5): 707-716, 2020 05 07.
Article in En | MEDLINE | ID: mdl-32386537
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Black or African American / Hispanic or Latino / Coronary Disease / Genetic Predisposition to Disease / Multifactorial Inheritance / White People Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male / Middle aged Language: En Journal: Am J Hum Genet Year: 2020 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Black or African American / Hispanic or Latino / Coronary Disease / Genetic Predisposition to Disease / Multifactorial Inheritance / White People Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male / Middle aged Language: En Journal: Am J Hum Genet Year: 2020 Type: Article Affiliation country: United States