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Potential SARS-CoV-2 Preimmune IgM Epitopes.
Shivarov, Velizar; Petrov, Peter K; Pashov, Anastas D.
Affiliation
  • Shivarov V; Laboratory of Clinical Immunology and Department of Clinical Hematology, Sofiamed University Hospital, Sofia, Bulgaria.
  • Petrov PK; Faculty of Biology, Sofia University, Sofia, Bulgaria.
  • Pashov AD; Department of Analysis, Geometry and Topology, Institute of Mathematics and Informatics, Bulgarian Academy of Sciences (BAS), Sofia, Bulgaria.
Front Immunol ; 11: 932, 2020.
Article in En | MEDLINE | ID: mdl-32425955
ABSTRACT
While studying the human public IgM igome as represented by a library of 224,087 linear mimotopes, three exact matches to peptides in the proteins of SARS-CoV-2 were found two in the open reading frame 1ab and one in the spike protein. Joining the efforts to fast track SARS-CoV-2 vaccine development, here we describe briefly these potential epitopes in comparison to mimotopes representing peptides of SARS-CoV, HCoV 229E and OC43.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin M / Betacoronavirus / Antibodies, Viral / Epitopes Limits: Humans Language: En Journal: Front Immunol Year: 2020 Type: Article Affiliation country: Bulgaria

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin M / Betacoronavirus / Antibodies, Viral / Epitopes Limits: Humans Language: En Journal: Front Immunol Year: 2020 Type: Article Affiliation country: Bulgaria