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Guanylate-binding proteins convert cytosolic bacteria into caspase-4 signaling platforms.
Wandel, Michal P; Kim, Bae-Hoon; Park, Eui-Soon; Boyle, Keith B; Nayak, Komal; Lagrange, Brice; Herod, Adrian; Henry, Thomas; Zilbauer, Matthias; Rohde, John; MacMicking, John D; Randow, Felix.
Affiliation
  • Wandel MP; Division of Protein and Nucleic Acid Chemistry, MRC Laboratory of Molecular Biology, Cambridge, UK. mwandel@mrc-lmb.cam.ac.uk.
  • Kim BH; Howard Hughes Medical Institute and Systems Biology Institute, Yale University, West Haven, CT, USA.
  • Park ES; Departments of Immunobiology and Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA.
  • Boyle KB; Howard Hughes Medical Institute and Systems Biology Institute, Yale University, West Haven, CT, USA.
  • Nayak K; Departments of Immunobiology and Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA.
  • Lagrange B; Division of Protein and Nucleic Acid Chemistry, MRC Laboratory of Molecular Biology, Cambridge, UK.
  • Herod A; Department of Paediatrics, University of Cambridge, Cambridge, UK.
  • Henry T; Department of Paediatric Gastroenterology, Hepatology and Nutrition, Cambridge University Hospitals, Addenbrooke's Hospital, Cambridge, UK.
  • Zilbauer M; CIRI, Centre International de Recherche en Infectiologie, University of Lyon, Inserm U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, University of Lyon, Lyon, France.
  • Rohde J; Department of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada.
  • MacMicking JD; CIRI, Centre International de Recherche en Infectiologie, University of Lyon, Inserm U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, University of Lyon, Lyon, France.
  • Randow F; Department of Paediatrics, University of Cambridge, Cambridge, UK.
Nat Immunol ; 21(8): 880-891, 2020 08.
Article in En | MEDLINE | ID: mdl-32541830
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Gram-Negative Bacterial Infections / GTP-Binding Proteins / Caspases, Initiator / Inflammasomes Limits: Animals / Humans Language: En Journal: Nat Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2020 Type: Article Affiliation country: United kingdom
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Gram-Negative Bacterial Infections / GTP-Binding Proteins / Caspases, Initiator / Inflammasomes Limits: Animals / Humans Language: En Journal: Nat Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2020 Type: Article Affiliation country: United kingdom