Strong association between the 12q24 locus and sweet taste preference in the Japanese population revealed by genome-wide meta-analysis.

Kawafune, Kaoru; Hachiya, Tsuyoshi; Nogawa, Shun; Takahashi, Shoko; Jia, Huijuan; Saito, Kenji; Kato, Hisanori

Kawafune, Kaoru; Hachiya, Tsuyoshi; Nogawa, Shun; Takahashi, Shoko; Jia, Huijuan; Saito, Kenji; Kato, Hisanori.

Affiliation

Kawafune K; Genequest Inc., Siba 5-29-11, Minato-ku, Tokyo, 108-0014, Japan.
Hachiya T; Genequest Inc., Siba 5-29-11, Minato-ku, Tokyo, 108-0014, Japan.
Nogawa S; Genome Analytics Japan Inc., 15-1-3205 Tomihisa-cho, Shinjuku-ku, Tokyo, 162-0067, Japan.
Takahashi S; Genequest Inc., Siba 5-29-11, Minato-ku, Tokyo, 108-0014, Japan.
Jia H; Genequest Inc., Siba 5-29-11, Minato-ku, Tokyo, 108-0014, Japan.
Saito K; Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.
Kato H; Genequest Inc., Siba 5-29-11, Minato-ku, Tokyo, 108-0014, Japan.

J Hum Genet ; 65(11): 939-947, 2020 Nov.

Article in En | MEDLINE | ID: mdl-32572145

Subject(s)

Aldehyde Dehydrogenase, Mitochondrial/genetics; Genetic Loci/genetics; Genome-Wide Association Study; Taste/genetics; Alcohol Drinking/genetics; Alcohol Drinking/pathology; Chromosomes, Human, Pair 12/genetics; Female; Genetic Predisposition to Disease; Genotype; Humans; Japan/epidemiology; Male; Middle Aged; Polymorphism, Single Nucleotide/genetics; Taste/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Taste / Genome-Wide Association Study / Genetic Loci / Aldehyde Dehydrogenase, Mitochondrial Type of study: Risk_factors_studies / Systematic_reviews Limits: Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: J Hum Genet Journal subject: GENETICA MEDICA Year: 2020 Type: Article Affiliation country: Japan

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