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Beta 1 integrin signaling mediates pancreatic ductal adenocarcinoma resistance to MEK inhibition.
Brannon, Arthur; Drouillard, Donovan; Steele, Nina; Schoettle, Shadae; Abel, Ethan V; Crawford, Howard C; Pasca di Magliano, Marina.
Affiliation
  • Brannon A; Medical Scientist Training Program, University of Michigan, Ann Arbor, USA.
  • Drouillard D; Department of Surgery, University of Michigan Cancer Center, University of Michigan, 1500 East Medical Center Drive, Cancer Center Room 6306, Ann Arbor, MI, 48109-0944, USA.
  • Steele N; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, USA.
  • Schoettle S; Department of Surgery, University of Michigan Cancer Center, University of Michigan, 1500 East Medical Center Drive, Cancer Center Room 6306, Ann Arbor, MI, 48109-0944, USA.
  • Abel EV; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, USA.
  • Crawford HC; Roswell Park Comprehensive Cancer Center, Elm & Carlton Streets, Buffalo, NY, 14263, USA.
  • Pasca di Magliano M; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, USA.
Sci Rep ; 10(1): 11133, 2020 07 07.
Article in En | MEDLINE | ID: mdl-32636409

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Integrin beta1 / MAP Kinase Signaling System / Carcinoma, Pancreatic Ductal Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Sci Rep Year: 2020 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Integrin beta1 / MAP Kinase Signaling System / Carcinoma, Pancreatic Ductal Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Sci Rep Year: 2020 Type: Article Affiliation country: United States