Simultaneous determination of eight bioactive components in Marsdenia tenacissima extract in rat plasma by LC-MS/MS and its application in a pharmacokinetic study.

Li, SiYu; Pei, Wen Han; Zhang, Hui

Li, SiYu; Pei, Wen Han; Zhang, Hui.

Affiliation

Li S; College of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian, P. R. China.
Pei WH; College of Traditional Chinese Medicine, Macau University of Science and Technology, Macau, China.
Zhang H; College of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian, P. R. China.

Biomed Chromatogr ; 34(11): e4946, 2020 Nov.

Article in En | MEDLINE | ID: mdl-32643816

Subject(s)

Chromatography, Liquid/methods; Drugs, Chinese Herbal; Marsdenia; Tandem Mass Spectrometry/methods; Animals; Cinnamates/analysis; Drugs, Chinese Herbal/chemistry; Drugs, Chinese Herbal/pharmacokinetics; Glycosides/analysis; Limit of Detection; Linear Models; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Steroids/analysis

Key words

LC-MS/MS; Marsdenia tenacissima (Roxb.) Wight et Arn; pharmacokinetic; plasma

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drugs, Chinese Herbal / Chromatography, Liquid / Marsdenia / Tandem Mass Spectrometry Type of study: Prognostic_studies Limits: Animals Language: En Journal: Biomed Chromatogr Year: 2020 Type: Article

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