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Pulmonary function in patients surviving to COVID-19 pneumonia.
Fumagalli, Alessia; Misuraca, Clementina; Bianchi, Achille; Borsa, Noemi; Limonta, Simone; Maggiolini, Sveva; Bonardi, Daniela Rita; Corsonello, Andrea; Di Rosa, Mirko; Soraci, Luca; Lattanzio, Fabrizia; Colombo, Daniele.
Affiliation
  • Fumagalli A; Respiratory Unit, IRCCS INRCA (Italian National Research Centre On Aging), 23880, Casatenovo, LC, Italy.
  • Misuraca C; Respiratory Unit, IRCCS INRCA (Italian National Research Centre On Aging), 23880, Casatenovo, LC, Italy.
  • Bianchi A; Respiratory Unit, IRCCS INRCA (Italian National Research Centre On Aging), 23880, Casatenovo, LC, Italy.
  • Borsa N; Respiratory Unit, IRCCS INRCA (Italian National Research Centre On Aging), 23880, Casatenovo, LC, Italy.
  • Limonta S; Radiology Unit, S. Leopoldo Mandic Hospital, 23807, Merate, LC, Italy.
  • Maggiolini S; Respiratory Unit, IRCCS INRCA (Italian National Research Centre On Aging), 23880, Casatenovo, LC, Italy.
  • Bonardi DR; Respiratory Unit, IRCCS INRCA (Italian National Research Centre On Aging), 23880, Casatenovo, LC, Italy.
  • Corsonello A; Unit of Geriatric Pharmacoepidemiology and Biostatistics and Unit of Geriatric Medicine, IRCCS INRCA (Italian National Research Centre On Aging), 87100, Cosenza, CS, Italy. a.corsonello@inrca.it.
  • Di Rosa M; Unit of Geriatric Pharmacoepidemiology and Biostatistics and Unit of Geriatric Medicine, IRCCS INRCA (Italian National Research Centre On Aging), 87100, Cosenza, CS, Italy.
  • Soraci L; Unit of Geriatric Pharmacoepidemiology and Biostatistics and Unit of Geriatric Medicine, IRCCS INRCA (Italian National Research Centre On Aging), 87100, Cosenza, CS, Italy.
  • Lattanzio F; Scientific Direction, IRCCS INRCA (Italian National Research Centre On Ageing), 60124, Ancona, AN, Italy.
  • Colombo D; Respiratory Unit, IRCCS INRCA (Italian National Research Centre On Aging), 23880, Casatenovo, LC, Italy.
Infection ; 49(1): 153-157, 2021 Feb.
Article in En | MEDLINE | ID: mdl-32725597
PURPOSE: The aim of our study was to assess respiratory function at the time of clinical recovery and 6 weeks after discharge in patients surviving to COVID-19 pneumonia. METHODS: Our case series consisted of 13 patients with COVID-19 pneumonia. RESULTS: At the time of clinical recovery, FEV1 (2.07 ± 0.72 L) and FVC (2.25 ± 0.86 L) were lower compared to lower limit of normality (LLN) values (2.56 ± 0.53 L, p = 0.004, and 3.31 ± 0.65 L, p < 0.001, respectively), while FEV1/FVC (0.94 ± 0.07) was higher compared to upper limit of normality (ULN) values (0.89 ± 0.01, p = 0.029). After 6 weeks pulmonary function improved but FVC was still lower than ULN (2.87 ± 0.81, p = 0.014). CONCLUSION: These findings suggest that COVID-19 pneumonia may result in clinically relevant alterations in pulmonary function tests, with a mainly restrictive pattern.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cough / Dyspnea / Fever / SARS-CoV-2 / COVID-19 / Lung Type of study: Diagnostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Infection Year: 2021 Type: Article Affiliation country: Italy

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cough / Dyspnea / Fever / SARS-CoV-2 / COVID-19 / Lung Type of study: Diagnostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Infection Year: 2021 Type: Article Affiliation country: Italy