Effect of dulaglutide on liver fat in patients with type 2 diabetes and NAFLD: randomised controlled trial (D-LIFT trial).

Kuchay, Mohammad S; Krishan, Sonal; Mishra, Sunil K; Choudhary, Narendra S; Singh, Manish K; Wasir, Jasjeet S; Kaur, Parjeet; Gill, Harmandeep K; Bano, Tarannum; Farooqui, Khalid J; Mithal, Ambrish

Kuchay, Mohammad S; Krishan, Sonal; Mishra, Sunil K; Choudhary, Narendra S; Singh, Manish K; Wasir, Jasjeet S; Kaur, Parjeet; Gill, Harmandeep K; Bano, Tarannum; Farooqui, Khalid J; Mithal, Ambrish.

Affiliation

Kuchay MS; Division of Endocrinology and Diabetes, Medanta-The Medicity Hospital, Haryana, India. drshafikuchay@gmail.com.
Krishan S; Department of Radiology, Medanta-The Medicity Hospital, Haryana, India.
Mishra SK; Division of Endocrinology and Diabetes, Medanta-The Medicity Hospital, Haryana, India.
Choudhary NS; Institute of Digestive and Hepatobiliary Sciences, Medanta-The Medicity Hospital, Haryana, India.
Singh MK; Department of Clinical Research and Studies, Medanta-The Medicity Hospital, Haryana, India.
Wasir JS; Division of Endocrinology and Diabetes, Medanta-The Medicity Hospital, Haryana, India.
Kaur P; Division of Endocrinology and Diabetes, Medanta-The Medicity Hospital, Haryana, India.
Gill HK; Division of Endocrinology and Diabetes, Medanta-The Medicity Hospital, Haryana, India.
Bano T; Division of Endocrinology and Diabetes, Medanta-The Medicity Hospital, Haryana, India.
Farooqui KJ; Division of Endocrinology and Diabetes, Medanta-The Medicity Hospital, Haryana, India.
Mithal A; Division of Endocrinology and Diabetes, Medanta-The Medicity Hospital, Haryana, India.

Diabetologia ; 63(11): 2434-2445, 2020 11.

Article in En | MEDLINE | ID: mdl-32865597

Subject(s)

Diabetes Mellitus, Type 2/drug therapy; Liraglutide/therapeutic use; Non-alcoholic Fatty Liver Disease/drug therapy; Alanine Transaminase/metabolism; Aspartate Aminotransferases/metabolism; Diabetes Mellitus, Type 2/metabolism; Glucagon-Like Peptides/analogs & derivatives; Humans; Hypoglycemic Agents/therapeutic use; Immunoglobulin Fc Fragments; Liver; Liver Function Tests; Non-alcoholic Fatty Liver Disease/metabolism; Recombinant Fusion Proteins

Key words

Controlled attenuation parameter; Dulaglutide; GLP-1 receptor agonists; Liver stiffness measurement; MRI-PDFF; MRI-derived proton density fat fraction; NAFLD; Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Pancreatic fat content

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diabetes Mellitus, Type 2 / Non-alcoholic Fatty Liver Disease / Liraglutide Type of study: Clinical_trials / Guideline Limits: Humans Language: En Journal: Diabetologia Year: 2020 Type: Article Affiliation country: India

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