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C9orf72 poly(GR) aggregation induces TDP-43 proteinopathy.
Cook, Casey N; Wu, Yanwei; Odeh, Hana M; Gendron, Tania F; Jansen-West, Karen; Del Rosso, Giulia; Yue, Mei; Jiang, Peizhou; Gomes, Edward; Tong, Jimei; Daughrity, Lillian M; Avendano, Nicole M; Castanedes-Casey, Monica; Shao, Wei; Oskarsson, Björn; Tomassy, Giulio S; McCampbell, Alexander; Rigo, Frank; Dickson, Dennis W; Shorter, James; Zhang, Yong-Jie; Petrucelli, Leonard.
Affiliation
  • Cook CN; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.
  • Wu Y; Neurobiology of Disease Graduate Program, Mayo Graduate School, Mayo Clinic College of Medicine, Rochester, MN 55902, USA.
  • Odeh HM; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.
  • Gendron TF; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Jansen-West K; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.
  • Del Rosso G; Neurobiology of Disease Graduate Program, Mayo Graduate School, Mayo Clinic College of Medicine, Rochester, MN 55902, USA.
  • Yue M; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.
  • Jiang P; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.
  • Gomes E; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.
  • Tong J; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.
  • Daughrity LM; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Avendano NM; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.
  • Castanedes-Casey M; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.
  • Shao W; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.
  • Oskarsson B; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.
  • Tomassy GS; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.
  • McCampbell A; Department of Neurology, Mayo Clinic, Jacksonville, FL 32224, USA.
  • Rigo F; Neurology Research, Biogen Idec, Cambridge, MA 02142, USA.
  • Dickson DW; Neurology Research, Biogen Idec, Cambridge, MA 02142, USA.
  • Shorter J; Ionis Pharmaceuticals, Carlsbad, CA 92010, USA.
  • Zhang YJ; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.
  • Petrucelli L; Neurobiology of Disease Graduate Program, Mayo Graduate School, Mayo Clinic College of Medicine, Rochester, MN 55902, USA.
Sci Transl Med ; 12(559)2020 09 02.
Article in En | MEDLINE | ID: mdl-32878979
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Frontotemporal Dementia / TDP-43 Proteinopathies / Amyotrophic Lateral Sclerosis Limits: Animals Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2020 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Frontotemporal Dementia / TDP-43 Proteinopathies / Amyotrophic Lateral Sclerosis Limits: Animals Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2020 Type: Article Affiliation country: United States