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Methylome-wide association study of central adiposity implicates genes involved in immune and endocrine systems.
Justice, Anne E; Chittoor, Geetha; Gondalia, Rahul; Melton, Phillip E; Lim, Elise; Grove, Megan L; Whitsel, Eric A; Liu, Ching-Ti; Cupples, L Adrienne; Fernandez-Rhodes, Lindsay; Guan, Weihua; Bressler, Jan; Fornage, Myriam; Boerwinkle, Eric; Li, Yun; Demerath, Ellen; Heard-Costa, Nancy; Levy, Dan; Stewart, James D; Baccarelli, Andrea; Hou, Lifang; Conneely, Karen; Mori, Trevor A; Beilin, Lawrence J; Huang, Rae-Chi; Gordon-Larsen, Penny; Howard, Annie Green; North, Kari E.
Affiliation
  • Justice AE; Department of Population Health Sciences, Geisinger, Danville, PA 17822, USA.
  • Chittoor G; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Gondalia R; Department of Population Health Sciences, Geisinger, Danville, PA 17822, USA.
  • Melton PE; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Lim E; School of Biomedical Science, Faculty of Health & Medical Sciences, The University of Western Australia, Perth, WA 6000, Australia.
  • Grove ML; School of Pharmacy & Biomedical Sciences, Faculty of Health Sciences, Curtin University, MRF Building, Perth, WA 6000, Australia.
  • Whitsel EA; Menzies Institute for Medical Research, College of Health & Medicine, University of Tasmania, Hobart, TA, 7000 Australia.
  • Liu CT; Department of Biostatistics, Boston University, Boston, MA 02118, USA.
  • Cupples LA; Human Genetics Center, Department of Epidemiology, Human Genetics & Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
  • Fernandez-Rhodes L; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Guan W; Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Bressler J; Department of Biostatistics, Boston University, Boston, MA 02118, USA.
  • Fornage M; Department of Biostatistics, Boston University, Boston, MA 02118, USA.
  • Boerwinkle E; Framingham Heart Study, Framingham, MA, 01701, USA.
  • Li Y; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Demerath E; Department of Biobehavioral Health, Pennsylvania State University, University Park, PA 16802, USA.
  • Heard-Costa N; Division of Biostatistics, University of Minnesota, Minneapolis, MN 55455, USA.
  • Levy D; Human Genetics Center, Department of Epidemiology, Human Genetics & Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
  • Stewart JD; Center for Human Genetics, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
  • Baccarelli A; Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX 77030, USA.
  • Hou L; Human Genetics Center, Department of Epidemiology, Human Genetics & Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
  • Conneely K; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA.
  • Mori TA; Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Beilin LJ; Department of Genetics, University of North Carolina at Chapel Hill, NC 27599, USA.
  • Huang RC; Division of Epidemiology & Community Health, University of Minnesota, Minneapolis, MN 55455, USA.
  • Gordon-Larsen P; Framingham Heart Study, Framingham, MA, 01701, USA.
  • Howard AG; Department of Neurology, Boston University School of Medicine, Boston, MA, 02118, USA.
  • North KE; Population sciences branch, NHLBI Framingham Heart Study, Framingham, MA 01702, USA.
Epigenomics ; 12(17): 1483-1499, 2020 09.
Article in En | MEDLINE | ID: mdl-32901515
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Methylation / Epigenesis, Genetic / Endocrine System / Adiposity / Epigenomics / Immune System Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Epigenomics Year: 2020 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Methylation / Epigenesis, Genetic / Endocrine System / Adiposity / Epigenomics / Immune System Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Epigenomics Year: 2020 Type: Article Affiliation country: United States