Protein Biomarkers for the Diagnosis of Alzheimer's Disease at Different Stages of Neurodegeneration.
Int J Mol Sci
; 21(18)2020 Sep 15.
Article
in En
| MEDLINE
| ID: mdl-32942527
ABSTRACT
Mainly obtained from familial Alzheimer's disease patients' data, we know that some features of the neurodegenerative start several years before the appearance of clinical symptoms. In this brief review, we comment on some molecular and cellular markers appearing at different stages of the disease, before or once the clinical symptoms are evident. These markers are present in biological fluids or could be identified by image techniques. The combined use of molecular and cellular markers will be of interest to determine the development of the different phases of the disease.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Biomarkers
/
Proteins
/
Neurodegenerative Diseases
/
Alzheimer Disease
Type of study:
Diagnostic_studies
Limits:
Animals
/
Humans
Language:
En
Journal:
Int J Mol Sci
Year:
2020
Type:
Article
Affiliation country:
Spain