Population-scale predictions of DPD and TPMT phenotypes using a quantitative pharmacogene-specific ensemble classifier.

Zhou, Yitian; Dagli Hernandez, Carolina; Lauschke, Volker M

Zhou, Yitian; Dagli Hernandez, Carolina; Lauschke, Volker M.

Affiliation

Zhou Y; Department of Physiology and Pharmacology, Karolinska Institutet, 17177, Stockholm, Sweden.
Dagli Hernandez C; Department of Physiology and Pharmacology, Karolinska Institutet, 17177, Stockholm, Sweden.
Lauschke VM; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of Sao Paulo, 05508-000, Sao Paulo, Brazil.

Br J Cancer ; 123(12): 1782-1789, 2020 12.

Article in En | MEDLINE | ID: mdl-32973300

Subject(s)

Algorithms; Dihydrouracil Dehydrogenase (NADP)/genetics; Genetic Variation; Methyltransferases/genetics; Benchmarking; Dihydropyrimidine Dehydrogenase Deficiency/genetics; Ethnicity; Genotype; Humans; Phenotype; Exome Sequencing/methods; Whole Genome Sequencing/methods

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Variation / Algorithms / Dihydrouracil Dehydrogenase (NADP) / Methyltransferases Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Br J Cancer Year: 2020 Type: Article Affiliation country: Sweden

Fulltext

XML

PubMed Links

Search on Google