To Remember or to Forget: The Role of Good and Bad Memories in Adoptive T Cell Therapy for Tumors.

Mondino, Anna; Manzo, Teresa

Mondino, Anna; Manzo, Teresa.

Affiliation

Mondino A; Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Manzo T; Department of Experimental Oncology, IRCCS European Institute of Oncology, Milan, Italy.

Front Immunol ; 11: 1915, 2020.

Article in En | MEDLINE | ID: mdl-32973794

Subject(s)

Immunologic Memory; Immunotherapy, Adoptive; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating/immunology; Neoplasms/therapy; T-Lymphocytes/transplantation; Adaptive Immunity; Animals; Cell Differentiation; Humans; Lymphocytes, Tumor-Infiltrating/metabolism; Neoplasms/immunology; Neoplasms/metabolism; Neoplasms/pathology; Phenotype; Signal Transduction; T-Lymphocytes/immunology; T-Lymphocytes/metabolism; Tumor Escape; Tumor Microenvironment

Key words

T cell; adoptive T cell immunotherapy of cancer; competition; memory; tumor immunity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphocyte Activation / T-Lymphocytes / Immunotherapy, Adoptive / Lymphocytes, Tumor-Infiltrating / Immunologic Memory / Neoplasms Limits: Animals / Humans Language: En Journal: Front Immunol Year: 2020 Type: Article Affiliation country: Italy

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