The Influence of Tobacco Smoke/Nicotine on CYP2A Expression in Human and African Green Monkey Lungs.

Gao, Yuan; Miksys, Sharon; Palmour, Roberta M; Tyndale, Rachel F

Gao, Yuan; Miksys, Sharon; Palmour, Roberta M; Tyndale, Rachel F.

Affiliation

Gao Y; Department of Pharmacology and Toxicology, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH) (Y.G., S.M., R.F.T.) and Department of Psychiatry (R.F.T.), University of Toronto, Toronto, Ontario, Canada and Department of Psychiatry and Human Genetics, McGi
Miksys S; Department of Pharmacology and Toxicology, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH) (Y.G., S.M., R.F.T.) and Department of Psychiatry (R.F.T.), University of Toronto, Toronto, Ontario, Canada and Department of Psychiatry and Human Genetics, McGi
Palmour RM; Department of Pharmacology and Toxicology, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH) (Y.G., S.M., R.F.T.) and Department of Psychiatry (R.F.T.), University of Toronto, Toronto, Ontario, Canada and Department of Psychiatry and Human Genetics, McGi
Tyndale RF; Department of Pharmacology and Toxicology, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH) (Y.G., S.M., R.F.T.) and Department of Psychiatry (R.F.T.), University of Toronto, Toronto, Ontario, Canada and Department of Psychiatry and Human Genetics, McGi

Mol Pharmacol ; 98(6): 658-668, 2020 12.

Article in En | MEDLINE | ID: mdl-33055223

Subject(s)

Aryl Hydrocarbon Hydroxylases/metabolism; Lung/pathology; Smoking/pathology; Steroid Hydroxylases/metabolism; Tobacco Smoke Pollution/adverse effects; Animals; Aryl Hydrocarbon Hydroxylases/analysis; Aryl Hydrocarbon Hydroxylases/genetics; Chlorocebus aethiops; Datasets as Topic; Disease Models, Animal; Gene Expression Profiling; Humans; Lung/drug effects; Lung Neoplasms/etiology; Lung Neoplasms/pathology; Lung Neoplasms/prevention & control; Male; Microsomes, Liver; Nicotine/toxicity; Non-Smokers; RNA, Messenger/analysis; Sequence Analysis, RNA; Smoke/adverse effects; Smokers; Smoking/adverse effects; Steroid Hydroxylases/analysis; Steroid Hydroxylases/genetics; Nicotiana/chemistry; Nicotiana/toxicity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Steroid Hydroxylases / Tobacco Smoke Pollution / Aryl Hydrocarbon Hydroxylases / Smoking / Lung Type of study: Etiology_studies Limits: Animals / Humans / Male Language: En Journal: Mol Pharmacol Year: 2020 Type: Article

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