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High temperature promotes amyloid ß-protein production and γ-secretase complex formation via Hsp90.
Noorani, Arshad Ali; Yamashita, Hitoshi; Gao, Yuan; Islam, Sadequl; Sun, Yang; Nakamura, Tomohisa; Enomoto, Hiroyuki; Zou, Kun; Michikawa, Makoto.
Affiliation
  • Noorani AA; Department of Biochemistry, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
  • Yamashita H; Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, Kasugai, Japan.
  • Gao Y; Department of Biochemistry, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
  • Islam S; Department of Biochemistry, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
  • Sun Y; Department of Biochemistry, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
  • Nakamura T; Department of Biochemistry, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
  • Enomoto H; Department of Biochemistry, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
  • Zou K; Department of Biochemistry, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan. Electronic address: kunzou@med.nagoya-cu.ac.jp.
  • Michikawa M; Department of Biochemistry, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan. Electronic address: michi@med.nagoya-cu.ac.jp.
J Biol Chem ; 295(52): 18010-18022, 2020 12 25.
Article in En | MEDLINE | ID: mdl-33067321
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Membrane / Amyloid beta-Peptides / Amyloid beta-Protein Precursor / HSP90 Heat-Shock Proteins / Amyloid Precursor Protein Secretases / Hot Temperature Limits: Animals / Female / Humans Language: En Journal: J Biol Chem Year: 2020 Type: Article Affiliation country: Japan
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Membrane / Amyloid beta-Peptides / Amyloid beta-Protein Precursor / HSP90 Heat-Shock Proteins / Amyloid Precursor Protein Secretases / Hot Temperature Limits: Animals / Female / Humans Language: En Journal: J Biol Chem Year: 2020 Type: Article Affiliation country: Japan