The Use of Near-Infrared Light-Emitting Fluorescent Nanodiamond Particles to Detect Ebola Virus Glycoprotein: Technology Development and Proof of Principle.

Feuerstein, Giora Z; Mansfield, Michael A; Lelkes, Peter I; Alesci, Salvatore; Marcinkiewicz, Cezary; Butlin, Nathan; Sternberg, Mark

Feuerstein, Giora Z; Mansfield, Michael A; Lelkes, Peter I; Alesci, Salvatore; Marcinkiewicz, Cezary; Butlin, Nathan; Sternberg, Mark.

Affiliation

Feuerstein GZ; Debina Diagnostics Inc., Newtown Square, PA, USA.
Mansfield MA; MilliporeSigma, Bedford, MA, USA.
Lelkes PI; Department of Bioengineering, Temple University, Philadelphia, PA, USA.
Alesci S; Debina Diagnostics Inc., Newtown Square, PA, USA.
Marcinkiewicz C; Debina Diagnostics Inc., Newtown Square, PA, USA.
Butlin N; Department of Bioengineering, Temple University, Philadelphia, PA, USA.
Sternberg M; Axxin Pty Ltd, Fairfield, VIC, Australia.

Int J Nanomedicine ; 15: 7583-7599, 2020.

Article in En | MEDLINE | ID: mdl-33116489

Subject(s)

Ebolavirus; Nanodiamonds/chemistry; Spectroscopy, Near-Infrared/instrumentation; Spectroscopy, Near-Infrared/methods; Viral Envelope Proteins/analysis; Animals; Antibodies, Monoclonal/immunology; Collodion; Ebolavirus/immunology; Enzyme-Linked Immunosorbent Assay; Fluorescent Dyes/chemistry; Humans; Immunoglobulin G; Membranes, Artificial; Mice; Proof of Concept Study; Viral Envelope Proteins/immunology

Key words

Ebola virus; LFA; OER; anti-EBOV antibodies; diagnostic lateral flow test; fluidics technology; nitrocellulose membranes; opto-electronic reader

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Envelope Proteins / Spectroscopy, Near-Infrared / Ebolavirus / Nanodiamonds Limits: Animals / Humans Language: En Journal: Int J Nanomedicine Year: 2020 Type: Article Affiliation country: United States

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